| A | B |
| epidemic | the rapid spreading of a disease to many people at the same time |
| epidermis | the outer skin |
| epigram | a short saying that makes its point in a witty way |
| epilogue | a part added at the end of a play or novel in which the author makes some comment |
| epistle | a serious letter. Also: When capitalized, any of the letters written by the apostles and included as books of the New Testament of the Bible. |
| epitaph | words carved on a tomb in memory of the person buried there |
| epithet | a descriptive word or phrase |
| epitome | a person or thing that is typical of or possesses to a high degree the features of something: He is the epitome of goodness |
| epiphany | flash of insight; twelve days after Christmas; celebrates the visit of the three wise men to the infant Jesus |
| ephemeral | lasting a very short time |