| A | B |
|---|
| removed "nuclein" from white blood cell nuclei | Miescher |
| completed the transformation experiment in which nonencapsulated bacterium became encapsulated | Griffith |
| identified DNA as the transforming substance using protease, ribonuclease and deoxyribonuclease | Avery, McLeod and McCarthy |
| used radioactive viruses to prove DNA is the genetic material | Hershey & Chase |
| developed the structural model of DNA | Watson & Crick |
| a nitrogenous base, pentose sugar and phosphate | nucleotide |
| adenine & guanine | purines |
| base of a single ring of 6 atoms | pyrimidines |
| cytosine, thymine and uracil | pyrimidines |
| base of a double ring of 6 atoms and an additional 3 | purines |
| a nitrogenous base and a pentose sugar | nucleoside |
| describes the repetative nature of DNA's molecule | polynucleotide |
| bond between sugars and phosphates | covalent |
| bond between bases | hydrogen bonds |
| the end of a DNA molecule which carries a phosphate | 5' |
| used X-ray crystallography to discover DNA's helical nature | Pauling, Wilkins, Franklin |
| discovered the 1:1 ratio of adenine to thymine then guanine to cytosine | Chargaff |
| protein type found in chromosomes | histones |
| 8 histones and 140 base pairs of DNA | nucleosome |
| DNA replication experiment | Meselson & Stahl |
| Molecules originally suspected of being the genetic material | protein, RNA, DNA |
| properties of proteins that made it a candidate for the genetic material | 1) abundant 2) made of 21 different amino acids (vs. DNA's 4 bases); allows for more variety |
| extra credit | e-mail me to say "Hey" (lpolhamus@bishopdwenger.com) |
| 1) able to replicate 2) able to hold large quantities of info 3) able to mutate 4) abundant | characteristics required of the genetic material |
