| A | B |
| Olmecs, Mayas, Aztecs, & Incas | the 4 oldest civilizations in the Americas |
| The Columbian Exchange | the exchange of animals, plants, cultures and diseases between the Old World and the New World (Americas) |
| King Ferdinand and Queen Isabella of Spain | financed Columbus's voyage in 1492 |
| Christopher Columbus | sailed west searching for a trade route to Asia and the Indies in 1492 |
| Oil and lumber | natural resources in the United States |
| Forests | resources used by the European colonists as raw materials that were also shipped back to England |
| Hernan Cortes | conquered the Aztec in Central Mexico |
| Francisco Pizzaro | conquered the Incas |
| Horses | brought over to the Americas by the Europeans |
| Great Plains Indians | buffalo was a very important resource |
| Northwest Coast Indians | used the river system for trading with other tribes and built totem poles to honor ancestors |
| Pueblo houses | were built by the Anasazi because it allows air to pass easily through the house for ventilation |
| Metacomet | known by the English as King Philip, and led the Wampanoag tribes in fighting back against the Puritans who were trying to take their land |
| Powahatan tribe | fought against the Jamestown colonists over land |
| Ferdinand Magellan | was the 1st explorer to sail around (circumnavigate) the world |
| Africans in New Spain | were first brought to the Americas and enslaved by the Spanish in the 1500s to replace the Indians |
| Africans in Jamestown | 1619 |
| Rocky Mountains | located in the western United States |
| Appalachian Mountains | located in the eastern United States |
| Great Plains | located in the middle of the United States |