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3.3.4 Vocabulary for HSA Review Packet

MD HSA 3.3.4

AB
InsertionMutation where an extra base is added. Example: Original: ATC-GCC. Mutant: AAT-CGC-C
SubstitutionMutation where the wrong base is added. Example: Original: ATC-GCC. Mutant: ACC-GCC
Somatic mutationMutation in a body cell. Can NOT be passed to offspring.
Germinal mutationMutation in the gamete. CAN be passed to offspring.
MutationsChange in the genes or chromosomes. Source of variation.
KaryotypePicture of all the chromosomes in a cell.
DeletionMutation in which a base is removed. Example: Original: ATC-GCC. Mutant: ACG-CC
Genetic engineeringManipulation of genes by scientists.
VariationDifferences within a species. Mutations are a source. Some are very beneficial--survive in a different or changing environment.
Gene splicingTechnique by researchers that "cuts" sections of DNA for use. Example: Creating bacteria to make human proteins to get a large amount of the proteins.
Chromosome number abnormalityChanges in chromosome number. Causes genetic disorders, like Down's syndrome. Occurs during meiosis--too many or too few chromosomes
Recombinant DNA (rDNA)DNA produced by combining DNA from two (or more) organisms. Ex: Bacterial DNA with human insulin gene
NondisjunctionProcess when one gamete receives both chromosomes and another gamete receives none. Happens during meiosis.
CloningMethod to develop organisms with desirable traits. Making organisms that have the same genes as the original.



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