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Biology (Lewis)--Genetics

AB
What are genetics?the branch of biology concerned with the ways in which hereditary information is transmitted from parents to offspring
A hybrid is...an individual that is heterozygous for a particular trait; an individual produced by a cross between members of two closely related species
F1 generation =parents
F2 generation =offspring
If a trait is dominant it means that...it appears in the offspring of a cross between two pure individuals showing contrasting forms of the trait
What is a recessive trait?a trait that is masked in the offspring of a cross between two pure individuals showing contrasting forms of the trait
What is the law of dominance?the principle of genetics stating that when organisms pure for contrasting traits are crossed, all their offspring show the dominant trait
The law of segregation is...the genetic principle stating that the alleles of a gene occur in pairs and are separated from each other during meiosis and are recombined at fertilization
A gene is...a distinct unit of hereditary material found in chromosomes; a sequence of nucleotides in DNA that codes for a particular tRNA, r RNA or polypeptide
What is an allele?one of the two or more forms of the gene for a specific trait
Having two identical alleles for a trait means that an organism is...homoozygous
A heterozygous organism is one that...has two different alleles for a trait
What is the genotype?the genetic make up of an individual
What is phenotype?the physical traits that appear in an individual as a result of its genetic makeup
A punnett square is used in genetics to...show the result of a cross
A monohybrid cross is...a genetic cross in which only one pair of contrasting traits is studied
A dyhybrid cross is...a genetic cross in which two pairs of contrasting traits are studied
What is a test cross?a genetic cross in which a test organism showing the dominant trait that is crossed with one showing the recessive trait
Incomplete dominance is...a type of inheritance in which neither pair of contrasting alleles is dominant over the other and the heterozygous individual is immediate in phenotype; blending inheritance
What is codominance?a type of inheritance in which two dominant alleles are expressed at the same time without blending of traits
Multiple alleles are...three or more different forms of a gene each producing a different phenotype
What are sex chromosomes?one of two unmatched chromosomes that determine the sex of an individual; represented as X and Y
What is an autosome?a chromosome other than a sex chromosome
A sex linked trait is...a trait that is controlled by a gene found on one of the six chromosomes
Color blindness is...a sex linked trait in which an individual cannot perceive certain colors
Gene linkage is...genes located on the same chromosome; they are not independently assorted but are distributed together during meiosis
In crossing over...pieces of homologous chromosomes are exchanged during synapsis in the first meiotic division
What is a mutation?the appearance of a new allele on a chromosome
What is gene mutation?a change in the sequence of the bases in a gene which changes the structure of the polypeptide that the gene codes for
Chromosomal mutations arechanges in chromosome structure resulting in new gene combinations
Translocation is...the transfer of a chromosome segement to a nonhomologous chromosome
An inversion is ..a type of chromosomal alteration in which a portion of a chromosome is rotated resulting in the reversal of the order of genes in that segment
An addition is...the breaking off of a chromosome segment and its attachment to the homologous chromosome
A deletion is...a type of chromosomal alteration in which a portion of a chromosome and the genes it contains is lost
Nondisjunction is...the failure of homologous chromosomes to separate normally during meiosis producing gametes or spores with one more or one less chromosome than normal
What is polyploidy?a condition in which the cells have the some multiple or the normal chromosome number
What is sickle cell anemia?a disease in which the red blood cells have an abnormal hemoglobin moleculre which gives the cells an abnormal shape which causes them to clump and block small blood vessels
What is PKU?a disease in which an enzyme necessary for the normal breakdown of the amino acid phenylalanine is missing; products of phenylalaning metabolism accumulate in the body damaging the brain and causing mental retardation
Tay-Sachs disease is the result from...the lack of an enzymen necessary for the breakdown of lipids in the brain.
Amniocentesis is...a technique in which amniotic fluid which contains fetal cells is withdrwn from the amniotic sac of a pregnant woman so the cells can be examined for the presence of genetic abnormalities
Four breeding methods are...selection, inbreeding, outbreeding, hybrid vigor/heterosis
Selection is...a technique in which only those animals and plants with the most desireable traits are chosen for breeding
Inbreeding is...when closely related individuals are mated to retain or strengthen certain desireable traits
Outbreeding is...when individuals not closely related are mated to introduce new beneficial alleles into the population
Hybrid vigor/heterosis is...superior characteristics that are often found in hybrids
DNA is made of of what chemical groups?5 carbon sugar(deoxyribose), phosphate group, 4 kinds of nitrogenous(nitrogen containing) bases
The composition and structure of RNA is...5 carbon sugar (ribose), and 4 bases are adenine, guanine, cytosine and uracil
What is the one gene, one enzyme hypothesis?Each gene produces its effects by controlling the synthesis of a particular enzyme
What is the function of mRNA?to carry the message for a single polypeptide in complementary form
What is transcription?the copying of a genetic message into a molecule of mRNA
What is a codon?each group of three bases that specifies an amino acid
What is transfer RNA (tRNA)?has only about 80 nucleotides--will pick up only one type of amino acid
What is an anticodon?the sequence of 3 bases that are complements of an mRNA codon
What is ribosomal RNA (rRNA)?RNA that is formed by DNA in the nucleoli of the cell
What is a gene mutation?a change in the sequence of the bases in a gene, which changes the structure of the polypeptide that the gene codes for
What is a natural mutation?all causes are not known--each type of mutation seems to occur at definite low rates in populations
What are mutagenic agents?factors in the environment that cause mutations (ex: x-rays, chloroform, mustard gas)
Name two types of gene mutations.When an entire nucleotide may be added or removed (ex: alkaptonuria, PKU) or when one base could be substituted
What is transformation?the transfer of DNA from dead, ruptured bacteria to living bacterial cells
What is transduction?the process in which pieces of DNA are transferred from one bacterial cell to another by viruses
What is recombinant DNA?DNA that has been altered by genetic engineering
Genetic engineering (gene splicing) isthe process of producing altered DNA usually by breaking a DNA molecule and inserting new genes
What is a plasmid?a small circular segment of DNA that is found in bacteria that stays separate from the bacterial chromosome; used in genetic engineering
What is a clone?a group of individual organisms that have identical genetic makeup
What is somaclonal variation?spontaneous genetic changes in cloning that results in many unexpected and useful genetic variations


Greenville High School

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