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Chapters 12, 13, 17 Review: DNA and Genetic Mutations

AB
In a nucleotide, to which deoxyribose carbon is the nitrogenous base attached?The 1' carbon. (one prime)
In a DNA strand, to which deoxyribose carbon is the succeeding nucleotide attached?The 3' carbon (three prime)
In which direction is DNA replicated?5' end toward 3' end
Name the pyrimidinesThymine and Cytosine
The pyrimidines contain __ ring(s).one
What are the parts of a nucleotide?A phosphate group, a sugar (deoxyribose), and a nitrogenous base
A three letter sequence on mRNA and DNA are known as a __.codon
The three letter sequence on a tRNA is known as an __.anticodon
Where does transcription occur?in the nucleus
Where does translation occur?in the cytoplasm (at ribosomes)
Messenger RNA is produced by the process of __.transcription
Proteins are made by the process of __.translation
Coding regions of DNA and mRNA are referred to as ___exons
In RNA splicing __ are removed.introns
The region of DNA that initiates the transcription of a gene is called the __.promoter
What type of bonding exists between nitrogenous bases?hydrogen
What type of bonding exists between nucleotides on the same strand?covalent
UV radiation causes primary lesions known as __.pyrimidine dimers
Chemicals cause primary lesions known as __.intercalating agents
Any substance that causes a mutation is called a __.mutagen
A termination signal or "terminator" causes __.termination of gene transcription
Excision repair is a way of repairing __.primary lesions
If primary lesions are not repaired, a __ occursmutation
A mutation is essentially a change in the __.DNA base sequence
Mutations involving one or few bases are known as __.point mutations
Single strand breaks are a type of __.primary lesion
A __ mutation has no effect on the resulting amino acid sequence.silent
A __ mutation changes the amino acid sequence of the resulting protein.missense
A missense mutation that does not affect the functioning of a protein is known as a __.neutral mutation
A chain-termination mutation is one that results in a __.stop codon
Mutations that are passed to offspring are called __.germ cell mutations
__ mutations cannot be inherited.Somatic
The enzyme __ produces new strands of DNA.DNA polymerase
A __ mutation results in a largely incorrect amino acid sequence.frameshift
Mutations in which large sections of DNA are inverted, lost, or added are known as __.chromosomal mutations
A chromosome fragment not containing a centromere is termed an __.acentric fragment
When a piece of chromosome breaks off and reattaches "upside down," it is called an __.inversion
__ are DNA segments that periodically move from one chromosome to another, i.e., "jumping genes."Transposons
Insertions or deletions cause __ mutations.frameshift
A __ is a segment of DNA that codes for a specific protein.gene
__ carries the genetic code to the ribosomes.mRNA
__ molecules transport amino acids to the ribosomes.tRNA
"Antiparallell" refers to the alignment of __.complementary DNA strands
The formation of mRNA is carried out by __.mRNA polymerase
DNA and mRNA are large molecules made of repeating units or __.polymers


Salem Community High School, Science Dept.
Salem, IL

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