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Resistance Of The Body To Infection - (copy)

Review - Week one-A

AB
Neurophils , eosinphils and basiophils arepolymorphnuclear cells
Polymorphonuclear neutrophils arethe most numerous cells among WBCs
Polymorphonuclear basophils arethe least numerous cells among WBCs
Granulocytes survive up to :4 – 8 hours in the blood 4-5 days in tissues
Monocytes survives up to10-20 hours in blood
Monocytes swell in the tissues sites and change intotissue macrophages
Lymphocytes survive up toweeks to months
Platelets are replaced withinabout 10 days
WBCs move through tissue spaces by WBCs move through tissue spaces byameboid movement
WBC are attracted toward inflamed areas bychemotaxis
WBCs enter the tissue bydiapedesis
Phagocytosing cells will eliminate objects that haverough surfaces, lack of the protective protein coat
Monocyte - Macrophage System is also known as:the reticuloendothelial system
Histocytes aretissue marcophages in the skin and subcutaneous tissue
kupffer cells aremarophages in the liver sinsoids
The immune system first line of defense against infectionis provided by the tissue macrophages
The Immune system second line of defense against infectionis provided by the neutrophil invasion of the infected area
The immune system third line of defense against infectionis provided by a second macrophage invasion into the inflamed tissue
The fourth line of defense aganist infectionsis provided by increasing the production of granulocytes and monocytes of the bone marrow
Pus is composed ofdead neutrophils, dead macrophages ncrosed tissue and tissue fluid
Eosinphils play a major role in defending the body in:Parasitic infections and allergic reactions
Basophils librateheparin
Leukopeniais reduced WBCs count
Leukocytosisis increased total number of WBCs
Myelogeous Leukemia is amalignant condition of the bone marrow
polymorphnuclear neutrophils consitute62% of the WBCs
polymorphnuclear esoinophils consitute2.3% of the WBCs
polymorphnuclear basophils consitute0.4% of the WBCs
monocytes consitute5.3% fo the WBCs
Particles phagocytoized by marcophages are digested mostly bylysosomes
"Walling-Off" in inflammation is a result ofblocking the area with fibrinogen clot
Acquired immunity depends onexposure to antigens
Lymphocytes are consideredthe basis of acquired immunity
metastatic growth of abnormal WBCs in abnormal sites occur inleukemias
GM-CSF stimulates the production ofgraulocytes and monocytes
Histamine is produced bythe mast cells
irriation by gamma rays could results inleukopnia
lymphocytic leukemia usually starts inlymph nodes
long standing metabolic starvation results indeath
formation of giant cells is a result ofmacrophages phagocytozing none digestable particles


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