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| Trade Name | Lomotil, Lonox |
| Generic Name | diphenoxyltae/atropine |
| Use: | treatment of diarrhea |
| Contraindications: | hypersensitivity; sever liver disease. Infectious diarrhea; colitis, dehydrated pts. |
| Side Effects: | dizziness, confusion, tachycardia, constipated, N/V, urinary rentention |
| Interactions: | additive CNS depression with other CNS depressants; alcohol, antihistamines, opoids, analgesics, and sedative hypnotics |
| Route/Dosage: | (Adults) PO 5 mg 3-4 times a day intially, then 5 mg once daily as needed. Do not exceed 20 mg/ day. (2.5mg diphenoxylate with 0.025mg of atropine) |
| Nursing Implications: | Assess frequency/consistency of stool & bowel sounds prior and during therapy. Assess pt fluid * electrolyte balance, skin turgor for dehydration. Liver function tests |
| Patient Teaching: | take as ordered, contact HCP if diarrhea persists, fever occurs, abd pain or palpatations. May cause drowsiness. Promote good oral hygiene. |
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