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Vermox
Classification: antihelmetics; Treats: Whipworm (trichuriasis), Pinworm (enterobiasis), Roundworm (ascariasis), Hookworm (uncinariasis) infections, Drug of choice for capillariasis
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| A | B |
| Trade Name | Vermox |
| Generic Name | mebendazole |
| Contraindications | Hypersensitivity.Use Cautiously in: Impaired liver function ,Crohn's ileitis , Ulcerative colitis |
| S/E | seizures, dizziness, headache, tinnitus, abdominal pain, diarrhea, increased liver enzymes, rash, urticaria, alopecia, agranulocytosis, reversible myelosuppression (leukopenia, thrombocytopenia), numbness, fever |
| Interaction | Carbamazepine and phenytoin may increase the metabolism and decrease effectiveness of therapy in patients receiving high-dose therapy. Absorption may be increased by fatty foods. |
| Adult dose | Enterobiasis:PO: (Adults and Children >2 yr): 100 mg as a single dose; repeat in 2–3 wk. Trichuriasis, Ascariasis, Hookworm, or Mixed InfectionsPO: (Adults and Children >2 yr): 100 mg twice daily for 3 days. If not cured in 3–4 wk, a 2nd course is given, Capillariasis PO: (Adults and Children >2 yr): 200 mg twice daily for 20 days |
| Nsg Implications | Pinworm: Perianal examinations should be performed to detect the presence of adult worms in the perianal area, and cellophane tape swabs of the perianal area should be taken before and starting 1 wk after treatment to detect the presence of ova. Swabs should be taken each morning before defecation or bathing for at least 3 days. Patients are not considered cured unless perianal swabs have been negative for 7 days. Roundworm: Stool examinations should be monitored before and 1–3 wk after treatment.Lab Test Considerations: May cause transient increase in serum BUN, AST, ALT, and alkaline phosphatase levels. Liver function tests should be monitored periodically during long-term therapy. CBC should be monitored before therapy and 2–3 times a week from day 10–25 and weekly thereafter in patients receiving high-dose or long-term therapy. Mebendazole may cause reversible leukopenia and thrombocytopenia. |
| Pt teaching | May cause dizziness. Caution patient to avoid driving or activities requiring alertness until response to medication is known. Pinworm: Instruct patient to wash (do not shake) all bedding, undergarments, towels, and nightclothes after treatment to prevent reinfection. |
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