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Vermox

Classification: antihelmetics; Treats: Whipworm (trichuriasis), Pinworm (enterobiasis), Roundworm (ascariasis), Hookworm (uncinariasis) infections, Drug of choice for capillariasis

AB
Trade NameVermox
Generic Namemebendazole
ContraindicationsHypersensitivity.Use Cautiously in: Impaired liver function ,Crohn's ileitis , Ulcerative colitis
S/Eseizures, dizziness, headache, tinnitus, abdominal pain, diarrhea, increased liver enzymes, rash, urticaria, alopecia, agranulocytosis, reversible myelosuppression (leukopenia, thrombocytopenia), numbness, fever
InteractionCarbamazepine and phenytoin may increase the metabolism and decrease effectiveness of therapy in patients receiving high-dose therapy. Absorption may be increased by fatty foods.
Adult doseEnterobiasis:PO: (Adults and Children >2 yr): 100 mg as a single dose; repeat in 2–3 wk. Trichuriasis, Ascariasis, Hookworm, or Mixed InfectionsPO: (Adults and Children >2 yr): 100 mg twice daily for 3 days. If not cured in 3–4 wk, a 2nd course is given, Capillariasis PO: (Adults and Children >2 yr): 200 mg twice daily for 20 days
Nsg ImplicationsPinworm: Perianal examinations should be performed to detect the presence of adult worms in the perianal area, and cellophane tape swabs of the perianal area should be taken before and starting 1 wk after treatment to detect the presence of ova. Swabs should be taken each morning before defecation or bathing for at least 3 days. Patients are not considered cured unless perianal swabs have been negative for 7 days. Roundworm: Stool examinations should be monitored before and 1–3 wk after treatment.Lab Test Considerations: May cause transient increase in serum BUN, AST, ALT, and alkaline phosphatase levels. Liver function tests should be monitored periodically during long-term therapy. CBC should be monitored before therapy and 2–3 times a week from day 10–25 and weekly thereafter in patients receiving high-dose or long-term therapy. Mebendazole may cause reversible leukopenia and thrombocytopenia.
Pt teachingMay cause dizziness. Caution patient to avoid driving or activities requiring alertness until response to medication is known. Pinworm: Instruct patient to wash (do not shake) all bedding, undergarments, towels, and nightclothes after treatment to prevent reinfection.



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