| A | B |
|---|
| Acquired B | Agglutinated by Griffonia simplicifolia lectin and monoclonal anti-B reagent containing the ES4 clone |
| Tn polyagglutination | Characteristic mixed field agglutination due to hematopoeitic clone mutation |
| Cad polyagglutinable RBC's | inherited type of polyagglutination capable of inhibiting anti-Sda and resist infection by Pasmodium falciparum. |
| Microbially induced polyagglutination | T, Th, Tk, . Tx. Acquired B, VA |
| Definition of Polyagglutination | abnormal RBC's are agglutinated by normal adult sera containing naturally occurring IgM antibodies that react with antigenic receptors that are normally hidden. |
| Common characteristics for microbially induced polyagglutinable RBC's | Associated with bacterial infection, agglutinated by Adult sera, Not agglutinated by cord sera, transient |
| Types of polyagglutination associated with decreased scialic acid (N-acetyl neuraminic acid) | T and Tn |
| Acquired B polyagglutination Mechanism | Bacterial deacetylace enzyme removes the N-acetyl group from N-acetylgalactoseamine (A antigen) converting it to Galactose (B antigen). Patients RBC's type strongly positive with Anti-A and weakly positive with anti-B. |
| Inherited types of polyagglutination | Cad, Hemoglobin M-Hyde Park, HEMPAS, NOR |
| HEMPAS polyagglutinable RBC's | RBC's have increased I antigen, decreased H antigen and are susceptible to increased lysis by anti-I and anti-i. |
| HEMPAS | Also known as Congenital Dyserythropoietic Anemia Type II (CDA Type II) |
| NOR polyagglutinable cells | NOR is an antigen in the P1Pk blood group system |
