| A | B |
|---|
| ++aminoglycosides ++ | narrow spectrum drugs from bacteria streptomyces |
| aminogycoside examples | streptomycin, gentamicin, tobramycin, amikacin |
| tetracyclines | very broad spectrum drugs that inhibit protein synthesis |
| tertracycline & chloramphenicol isolated from-- | bacteria strepromyces |
| tetracycline and chloramphenicol | interfere with translation--use is limited because of severe side effects |
| erythromycin & clindamycin | both affect protein synthesis |
| erythromycin--uses | broad-spectrum often used for those microbes resistant to PCN |
| clindamycin-uses | primarily for intestinal ifection by anaerobes |
