| A | B |
|---|
| The Most Prevalent Enteric Bacillus | Escherichia coli (e-coli) |
| enteric | having to do with GI tract |
| Escherichia coli (e-coli) | Most common aerobic bacterium in gut --150 strains-- Some have developed virulence through plasmid transfer, others are opportunists |
| Enterotoxigenic E. coli | causes severe diarrhea due to heat-labile toxin and heat-stable toxin |
| Enteroinvasive E. coli | causes inflammatory disease of the large intestine |
| Enteropathogenic E. coli | linked to wasting form infantile diarrhea |
| Enterohemorrhagic E. coli | causes hemorrhagic syndrome and kidney damage |
| ___________Pathogenic strains frequent agents of infantile diarrhea – greatest cause of mortality among babies | Escherichia coli (e-coli) |
| ______Causes ~70% of traveler’s diarrhea | Escherichia coli (e-coli) |
| _______Causes 50-80% UTI | Escherichia coli (e-coli) |
| Coliform count | – indicator of fecal contamination in water |
| Typhoid Fever-how transmitted | Bacillus enters with ingestion of fecally contaminated food or water; occasionally spread by close personal contact |
| Salmonella typhi – | most serious pathogen of the genus; cause of typhoid fever; human host |
| Flagellated; survive outside the host Resistant to chemicals – bile and dyes | Salmonella typhi – |
| Typhoid Fever-disease progress | Bacilli adhere to small intestine, cause invasive diarrhea that leads to septicemia |
| typhoid fever treatment | Treat with chloramphenicol or sulfatrimethoprim 2 vaccines for temporary protection |
| enteric fevers | Salmonelloses other than typhoid fever |
| enteric fevers examples | Salmonella food poisoning, and gastroenteritis--Usually less severe than typhoid fever but more prevalent |
| Shigellosis – | incapacitating dysentery |
| S. dysenteriae, S. sonnei, S. flexneri, and S. boydii | Human parasites- Invades villus of large intestine, does not perforate intestine or invade blood |
| Shigellosis treatment | Treatment – fluid replacement and ciprofloxacin and sulfatrimethoprim |
| If your nephew gets gastroenteritis after cleaning out his pet snake’s aquarium, the most likely pathogen is Shigella dysenteriae Serratia marcescens Salmonella typhi Salmonella enteritidis | Salmonella enteritidis |
| Coagulase-- Endotoxin-- Murine toxin | Virulence factors – capsular and envelope proteins protect against phagocytosis and foster intracellular growth |
| Yersinia pestis | Humans develop plague through contact with wild animals (sylvatic plague) or domestic or semidomestic animals (urban plague) or infected humans |
| Most dangerous form of plague: | pneumonia |
| Yersinia pestis | Found in 200 species of mammals – rodents, without causing disease |
| Yersinia pestis | Flea vectors |
| types of plaque | Bubonic ,Septicemic ,Pneumonic |
| bubo | necrosis and swelling in groin or axilla |
| The bubo of bubonic plague is a/an Ulcer where the flea bite occurred --Granuloma in the skin-- Enlarged lymph node-- Infected sebaceous gland | Enlarged lymph node |
