| A | B |
| Duke of York | Largest land owner in America, once controlled New York and New Jersey |
| Royal Colony | A colony run directly by the King or Queen |
| Breadbasket Colony | Nickname given to the middle colonies because of all the grain that the produced |
| Delaware River | Body of water separating Pennsylvania and New Jersey, an important river running through Philadelphia |
| Immigrant | People who move from one country to another |
| Melting Pot Colony | Nickname given to the middle colonies because of all the nationalities that found safe refuge there |
| Proprietor | An owner |
| Quaker | Religious order that came to Pennsylvania, lead by William Penn |
| William Penn | Proprietor and governor of the Delaware and Pennsylvania colonies |
| English Bill of Rights | Law that stated that English law is to be passed by Parliament, not a King |
| Salem Witch Trials | Series of events in Salem, Massachusetts that lead to the execution of those thought to be possessed by the devil |
| Middle Passage | The route taken by slaves between Africa and the West Indies |
| Act of Tolerance | Act passed in the colony of Maryland allowing for the practice of Catholicism |
| Lord Baltimore | Founder of the colony of Maryland |
| House of Burgesses | The first representative assembly (government) in the Jamestown colony |
| Indentured Servant | Someone who pays off their debt for passage to America |
| Plantations | Large farms used to grow cash crops |
| tobacco | Main cash crop of the Jamestown colony |
| Malaria | Disease caused by mosquitoes, usually contracted in and around swampy areas |
| James Oglethorpe | The founder and proprietor of the Georgia colony |
| New Netherlands | Original Dutch name of the colony of New York |
| Pennsylvania Dutch | German born immigrants who moved to Pennsylvania to settle |
| Parliament | The ruling body of England |
| Catholics | Religious group that found a safe haven in Maryland |
| John Smith | The first governor of the Jamestown colony |
| Bees and Frolics | The act of mixing games with work in colonial America |
| Debtor | Those who owed money to others |
| Cricket | A baseball like game that was played in the colonies |
| Magna Carta | Document signed in 1215 that limited the power of the English King |
| Slavery | The involuntary servitude of one person over another |