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GeneticsEscalon

Review important terms from classical, modern, and applied genetics.

AB
Law of DominanceWhen an organism is hybrid for a pair of contrasting traits, only the dominant trait can be seen in the hybrid.
Law of Segregationfactors (genes) that occur in pairs are separated from each other during meiosis and recombined at fertilization
chromosomesgenes are found on these structures
genea sequence of nucleotides in DNA that codes for a particular protein
allelesdifferent forms of the same gene (ex: T or t)
homozygouscontaining two alleles that are the same (ex: tt or TT)
heterozygouscontaining two alleles that are different (ex: Tt)
genotypethe genetic makeup of an organism (ex: Tt)
phenotypethe physical trait that an organism develops as a result of its genotype (ex: tall)
Law of Independent AssortmentDuring meiosis, genes for different traits are separated and distributed to gametes independently of one another
incomplete dominanceoccurs when two alleles contribute to the phenotype;traits blend
codominanceboth traits are expressed at the same time
multiple allelesmore than two alleles for the same trait (ex:blood type in humans)
genotype of a maleXY
genotype of a femaleXX
sex chromosomeschromosomes that determine the sex of an organism
sex-linked traitstraits that are controlled by genes on the sex chromosomes (usually the X)
examples of sex-linked traits in humanshemophilia, color-blindness
crossing-overpieces of homologous chromosomes are exchanged during meiosis
DNA replicationforms two new molecules of DNA, each with one old strand and one new strand
messenger RNAa strand of RNA that copies a genetic message from DNA
codona group of three bases on mRNA that specifies an amino acid
transfer RNAa molecule of RNA that carries an amino acid to the ribosome in order to assemble a protein
anticodona sequence of 3 bases in tRNA that is complementary to the codon of mRNA
transcriptionthe formation of codons by the mRNA
translationprocess by which information in mRNA is used by tRNA to assemble a protein
mutationsudden change in structure or amount of DNA
types of chromosomal mutationsaddition, deletion, translocation, inversion, nondisjunction, polyploidy
types of gene mutationspoint mutation, frameshift mutation
chromosomal mutationchange in the structure of all or part of a chromosome
gene mutationchange that affects a gene on a chromosome
mutagensenvironmental factors that cause mutations
nondisjunctionthe addition or loss of a whole chromosome due to failure of homologous chromosomes to separate during meiosis
point mutationsubstitution of one nucleotide for another, resulting in change in one codon, one amino acid
frameshift mutationdeletion or addition of a nucleotide, resulting in change in every codon after that point
human chromosomal disordersDown syndrome, Klinefelter's syndrome, Turner's syndrome
karyotypea chart showing all of an organism's chromosomes, arranged in homologous pairs
genetic engineeringmanipulation of DNA to produce changes in an organism
restriction enzymesenzymes used to cut DNA into fragments in order to isolate a gene
recombinant DNADNA formed by inserting a gene from one organism into the DNA of a different organism
gene therapyreplacement of defective genes by transferring normal genes into cells that lack them
genomeall of the genes possessed by an organism
pedigreechart that shows the lineage of a particular trait


Biology Teacher
McNeil High School
Austin, TX

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