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The Cell Cycle (growth & division)

The normal stages of the life of a somatic cell from interphase through mitosis, and what can happen when this process goes array (cancer).

AB
Why does a cell need to divide?It cannot perform its functions efficiently if it gets too large
cell life cycleincludes interphase and mitosis
interphaseabout 94% of the cell's life is spent in this phase
mitosisabout 6% of the cell's life is spent in this phase
stages of interphaseGap 1 (G1), Synthesis (S), and Gap 2 (G2)
stages of mitosisProphase, Metaphase, Anaphase, Telophase, Cytokinesis
Gap 1 (G1)stage when most cell growth, organelle replication, and cell activity occurs
Synthesis (S)stage when the cell's DNA is copied inside the nucleus
Gap 2 (G2)stage when the cell makes final preparations and checks for errors in DNA for the next stage (mitosis)
Prophasechromosomes condense and become visible in the center of the cell, and centrioles form the microtubules (spindle fibers) that will eventually guide chromosome division; nucleolus disappears
Metaphasechromosomes line up down the middle of the center of the cell, and spindle fibers attach to the centromeres on each set of sister chromatids
Anaphasecentromeres split, and sister chromatids split apart as the spindles start to pull chromosomes to opposite ends of the cell
Telophasespindle fibers break apart, and a nuclear membrane begins to develop and surround each cluster of chromosomes at opposite ends of the cell; the nucleolus also reappears
chromatinDNA in the form of strands, gathered up like a ball of yarn in the cell's nucleus
chromatida duplicated chromosome; one of the two identical copies of DNA that when with its matching "twin", will make "sister chromatids"
sister chromatidsset of identical chromatids, attached together by a centromere
chromosomeDNA that has been condensed, by being wrapped up around histones, and coiled up tightly to become thicker and shorter during M phase.
centromerethe region on a chromosome that joins two sister chromatids
cancerous cellscells that grow and divide out of control
metastatic cellscancerous cells that can travel through the blood stream and lymph vessels from one part of the body to another, infecting new areas with cancerous cells
cytokinesisThe cell membrane closes inward splitting the cell into two daughter cells. Daughter cells are genetically identical.
the uncontrolled growth of abnormal cells in the bodyWhat is cancer?
carcinogena substance known to be directly involved in causing cancer
mutationserrors that can occur in DNA that can lead to cancerous cells
chemotherapythe use of chemicals to try and stop cancerous cells from growing
stem cellA cell that is able to develop into any type of cell found in a particular organism
a differentiated cella cell has become different from the embryonic cell that produced it
differentiationthe process by which cells become specialized
approximately 100 trillionthe number of cells in the human body
embryothe early stage of development of an organism
zygotea fertilized egg; becomes a blastocyst, then an embryo
asexual reproductionthe production of identical offspring fro a single parent
sexual reproductioninvolves the fusion of 2 separate parent sex cells; offspring inherit genetic info from each parent
centriolesorganelles outside of the nucleus that make spindle fibers to be used during Mitosis
spindle fibersdevelop from the centrioles; attach to the centromeres of chromosomes to pull apart chromatids during anaphase of Mitosis
apoptosisthe process of programmed cell death
Meiosisthe formation of gametes
form a zygote that develops into a new individual2 gametes
haploid cellsex cells - 1 set of chromosomes
crossing overan exchange of DNA that occurs during Meiosis 1
tetrada pair of homologous chromosomes that will cross over
diploid cellsbody cells - 2 sets of chromosomes


math & science teacher
Academy of the New Church Girls School
Bryn Athyn, PA

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