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Psychopharmacology

AB
PhenothiazinesAntipsychotics assoc'd w/ releif of "+" sx, such as delusions & hallucinations.
AntipsychoticsDrus used to treat sx of schizophrenia. Anticholinergic & extrapyramidal side effects.
NeurolepticsAntipsychotic drugs to treat schizophrenia.
AntidepressantsDrugs used to elevate mood. Increase brain levels of norepinephrine &/or serotonin and treat panic and agoraphobia.
TricyclicsAntidepressants that reduce br levels of norepinephrine & serotonin.
ImipramineTofranil, Tricyclic: blocks reuptake of norepinephrin/serotonin., more available in synapse.
ClomipramineAnafranil, Tricyclic: reduces norepinephrine/serotonin...
Thorazinechlorpromazine: neuroleptic.
Mellarilthioridazine: neuroleptic.
Haldolhaloperidol: neuroleptic.
Clorazilclozapine: newer, atypical., no TD. Risk: white blood cells.
SSRI'sAntidepressants class. Incr brain serotonin levels. Fewer side effects than tricyclics. not cardiotoxic, safe in OD, no cog impairment, few anticholinergic side effects. More rapid onset than tri.
Prozacfluoxetine
Zoloftsetraline
Paxilparoxetine
MAOI'sAntidepressants that impair enzyme monomine oxidase, which degrades norepinephrine. No tyramine foods. SE: hypotension, dizzy, drymouth, upset stomach, incr wt, blurr vision, HA... Elevated BP, convulsions.
Tyramine foodsbeer, wine, aged cheese, beef/chicken liver, smoked meat, packaged soup, soy sauce, sour cream, avocados, bananas, plums, raisin, eggplant, spinach, tomatoes, yogurt.
Nardilphenelzine (MAOI)
Parnatetranylcypromine (MAOI)
LithiumFor bipolar d/o. decr mania, moodswings. also for schizophrenia, intermittant expl d/o and episodic binge drinking.
Tegretolcarbamazepine. For mania, dyspohric maina and rapid cycling.
DepakoteValproic Acid, Anticonvulsant drug for mania etc.
NeurotransmittersChemicals released by neurons to communicate w/other neurons causing either excitation or inhibition of neuron's activity.
Norepinephrineneurothransmitter 1 Involved in mania. A catecholamine, with dopamine.
DopamineNeurotransmitter 2, Involved in Parkinsons, insufficient in basal ganglia. too much: Schizophrenia.
Serotoninneurotransmitter 3, implicated in mental disorders such as mood d/o & schizophrenia.
AcetylcholineNeurotransmitter 4
Glutamateneurotransmitter 5
Benzodiazepinesclass of anti-anxiety meds: enhance GABA activity, inhibits CNS.
XanaxAlprazolam: antianxiety meds.
Valiumdiazepam: antianx med.
Halciontriazolam: antianx med.
Beta Blockersreduce receptivity of beta-andrenergic neurons (innervate cardiovascular/respiratory sx). performance, migraines, cardiac arrythmia, hypertension, essential tremor.
Inderolpropranolol, Beta blocker anx performance med
BarbituatesCNS depressant, interrupt impulses to RAS. Rare today. Dangerous and addictive. Anx.
Pentothalthiopental Barbituate, gen anesthetic
Amytalamobarbitol, bartituate, for acute agitation.
Seconalsecobarbital, barbituate
MethylphenidateRitalin, CNS stimulant for ADHD
Catecolaminedepression is due to deficient brain levels of norepinephrine, a cat. w/ epinephrine and dopamine
Tardive DyskinesiaInvol. rhythmic mvmt face/tongue/jaw occur w/phenothiazines. Delayed effect of antipsychotic use, 6 mo+, irreversable but younger pts can be alleviated w/grad w/d, w/temp incr. sx.
REM reboundIncr ReM sleep occurs when stop barbituates. REM sleep: cortical arousal, rapid eyemovements/dreaming.
Serzonenefazodone, works on serotonin
Wellbutrinbupropion
Ascendinamoxapine, tricyclic
Celexacitalopram
Norpraminedesipramine, Tricyclic
Vivactylprotriptyline, tricyclic, blocks norepinephrine
Desyreltrazodone, misc, serotonin
Effexorvenlafaxine, misc, norephinephrine, serotonin
Tricyclic side effectsDizzy, drowsy, dry mouth, HA, Wt incr, photosensitivity
MAOI side effectsdizzy, orthostatic hypotension, can't see/spit/pee/shit, mild HA, wt incr, insomnia.
Toxic side effects, TricyclicsSevere drowsy, confusion, hallucinations, siezures, tachycardia, bradycardia, diff breathing
Toxic side effects, MAOISevere drowsy/dizzy, hyper/hypotension, tachicardia, diff sleeping, hallucinations, respiratory depr.


Ms. McEwan

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