A | B |
hormone | chemical signal carries by circulatory system |
endocrine glands | organs that synthesize and secrete hormones |
endocrine system | group of organs for communication and chemical regulation |
target cells | cells with receptors to respond to particular hormones |
local regulators | chemical signals affecting ONLY nearby target cells |
neurosecretory cells | perform as both electrical and chemical signalers |
protein (hydrophilic) hormones | cannot pass through cell membranes must activate a membrane receptor |
lipid (hydrophobic) hormones | can pass through membranes to activate a receptor in cell cytoplasm |
reception | hormone binding to membrane or cyplasm receptor |
signal transduction | signal amplification by setting off a cascading series of reactions |
response | change in cell behavior initiated by hormone |
steroid hormones | mainly sex hormones derived from cholsterol |
hypothalamus | region of brain with neurosecretory cells interface of nervous/endocrine systems |
TSH releasing hormone (TRH) | hypothalamus secretion stimulates release of TSH |
oxytocin | hypothalmic peptide hormone stimulates contractions of uterine contractions of uterus and mammary gland |
antidiuretic hormone (ADH) | hypothalmic peptide hormone stimulate water retention in kidneys |
pituitary gland | master gland secretes controlling hormones |
pituitary posterior lobe | stores and secretes hypothamic oxytocin and ADH |
pituitary anterior lobe | synthesizes and secretes pituitary hormones |
releasing hormones | induce pituitary to synthesize/secrete hormones |
inhibiting hormones | induce pituitary to stop synthesizing/secreting hormones |
endorphins | pituitary hormones that bind to neuron receptors to reduce pain |
growth hormone (GH) | pituitary peptide hormone stimulate bone growth and general metabolis |
gigantism | disease caused by excess secretion of growth hormone |
acromegaly | disease caused by excess secretion of growth homrmone after puberty |
pituitary dwarfism | disease of deficiency of growth hormone secretion |
prolactin (PRL) | pituitary peptide hormone stimulates milk production |
follicle stimulating hormone (FSH) | pituitary peptide hormone stimulates ova/sperm production |
luteinizing hormone (LH) | pituitary peptide hormone stimulates ovary/testis functions |
thyroid stimulating hormone (TSH) | pituitary peptide hormone stimulates thyroid gland secretions |
adrenocorticotropic hormone (ACTH) | pituitary peptide hormone stimulates adrenal glucocoticoid secretion |
pineal gland | produces amine hormone melatonin |
melatonin | controls circadian rhythms |
thyroid gland | produces hormones controling metabolism/calcium levels |
thyroxine | amine hormone stimulates/maintains metabolic processes |
hyperthyroidism | thyroxine excess fast basal metabolism, nervous, weight loss |
Graves’ disease | thyroxine excess fluid accumuation behind eyeballs |
exophthalmia | excess thyroxine symptom of "bulging eyeballs" |
hypothyroidism | deficiency of thyroxine weight gain, lethargy, goiter |
goiter | iodine deficiency accumulation of stored thyroxine swelling gland |
calcitonin | blood [Ca+] high, stimulate uptake from blood into bones |
antagonistic hormones | hormones that have opposit effect (calcitonin & parathyroid hormone) |
parathyroid gland | patches of glandular tissue on thyroid surface secrete parathyroid hormone |
parathyroid hormone (PTH) | blood [Ca+] low, releases Ca+ from bones to blood |
thymus gland | gland large in childhood, found beneath breast bone, secretes thymosin |
thymosin | thymus peptide hormone stimulates T-cell development |
adrenal gland | endocrine gland founr atop the kidneys |
adrenal medulla | central portion of adrenal gland secrete "flight/fight" hormones |
epinephrine | adrenal amine hormone increases blood glucose/metabolism/constrict blood vessels |
norepinephrine | same effects as epinephrine but to lesser degree |
adrenal cortex | outer region secretes corticosteroids |
glucocorticoids | adrenal steroid increases blood glucose levels |
cortisone | adrenal steroid accelerates tissue repair/growth |
mineralcorticoids | adrenal steroid promotes kidney reabsorption of sodium excretion of potassium in kidney |
aldosterone | adrenal mineralcorticoid hormone |
pancreas | endocrine and exocrine gland involved in sugar metabolism |
insulin | pancreatic protein hormone removes sugar from blood |
diabetes mellitus | autoimmune disease with deficiency of insulin production causes high blood sugar levels |
hypoglycemia | excess production of insulin causes low blood sugar levels |
glucagon | pancreatic peptide hormone releases sugar into blood |
testis | male reproductive/endocrine organ |
androgens | testicular steroid hormones stimulate development/maintenance of male reproductive system |
testosterone | androgen responsible for male secondary sex characteristics |
ovary | female reproductive endocrine organ |
estrogen | ovarian steroid hormone stimulates development and maintenance of female systems |
progesterone | ovarian steroid hormone prepares and maintains uterus during pregnancy |
Type 1 insulin dependent diabetes | autoimmune dstruction of beta cells stops insulin production |
Type 2 non-insulin dependent diabetes | target cells receptiors decrease response to insulin being produced |
gestational diabetes | insulin deficiency during pregnancy can result in dangerously large babies |