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Nexium - Gastric Acid Pump Inhibitor
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| A | B |
| Trade Name | Nexium |
| Generic Name | Esomeprazole |
| Use | GERD, erosive esophagus, decrease risk of gastric ulcer during continuous NSAID therapy. |
| Contraindications | Concurrent use of atazanavir and nelfanair. Use cautiously in severe hepatic impairment & patients using high dosage for >1 year. |
| Side Effects | Headache, psuedomembranous colitis, abdominal pain, constipation, diarrhea, dry mouth, nausea, hypomagnesia, bone fracture. |
| Interactions | May decrease levels f atazonavir and nelfanair. May increase levels of toxicity of saquinavir, may increase risk of bleeding with warfarin. |
| Dosage | 20mg, 40mg, 10mg, 5mg |
| Nursing Implications | Assess for epigastric or abdominal pain and occult blood in stool, emesis or gastric aspirate. Monitor bowel function. May cause increase in serum creatine, bilirubin, potassium & serum sodium. May alter hemoglobin, WBC, platelets. May cause hypomagnemia |
| Teaching | Take as directed, avoid alcohol products and products that contain aspirin or NSAIDS, and foods that may cause an increase in GI irritation. Report black tarry stools, diarrhea, abdominal pain or persistent headache. |
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