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Pathophysiology: GI

AB
Nausea is a subjective or objective finding?Nausea is subjective - it's what the patient says it is
What are common causes of constipation?Decreased fiber, decreased fluids, hypothyroidism, aging, sedentary lifestyle
A patient has had diarrhea for 2 weeks. It is acute or chronic?Acute last to three weeks, > 3 weeks it's chronic
What are the ANS symptoms of vomiting?Decreased BP, tachycardia, sweating, salivation
Dysphagia is caused by?Alterations in cranial nerves, neurological impairments, strictures of the esophagus, scleroderma, esophageal cancer
What is the cause of GERD?A week or incompetent lower esophageal sphincter (LES) which is also called the cardiac sphincter
GERD increases the risk of developing ___________ which can lead to esophageal cancer.Barrett's Esophagus
What is acute gastritis? Is it permanent?Acute gastritis is an inflammation of the gastric mucosa due to irritants. Remove the irritant then it will resolve.
What is a common cause of chronic gastritis?Helicobacter pylori (H. pylori) is the most common but also autoimmune disease
Gastrointestinal bleeding puts the patient at risk for?Hypovolemic shock
What is hematemesis?Blood in vomit
What is coffee ground emesis?Blood in vomit
What is hematochezia?Bright red stools
What is melena?Black tarry stools
Which disorder can be caused by psychological distress?IBS (Irritable bowel syndrome)
What is steatorrhea?Fat in stool due to impaired fat absorption
In which disorder will the mucosal layer of the intestines have pinpoint hemorrhages?Ulcerative colitis
What's a fistula?Abnormal connection between two hollow spaces
___________ is continuous and ___________ has skip lesions (noncontinuous)Ulcerative colitis is continuous. Crohn's Disease is noncontinous granulomas (cobble stone looking)
What causes infectious enterocolitis when Clostridium deficile is implicated?Likely caused by antibiotic therapy
What causes Escherichia coli infectious enterocolitis?feces, contaminated foods
How does diverticulosis differ from diverticulitis?Diverticulitis is an inflammation of the diverticulum. Will have a fever and elevated WBCs
What is a complication of diverticulitis?Peritonitis
What is the hallmark sign of peritonitis?Board like, rigid abdomen
What are some manifestations of appendicitis?Abrupt onset lower abdominal pain which can be referred to the epigastric or periumbilical area, febrile, elevated WBCs, rebound tenderness
If a patient has an incomplete fecal impaction you might see?Watery stool
What is a volvulus?An obstruction caused by twisting of stomach or intestines
What is intussusception?Telescoping of the intestines. Most common obstruction in children less than 2
What are some causes of mechanical intestinal obstructions?Foreign bodies (surgical items), postop adhesions, strictures, tumors, intussusception, volvulus
What is borborygmus?Rumbling sounds made by the propulsion of gas in the intestines
What some manifestations of an intestinal obstruction?Abdominal distention, absolute constipation, borborygmus, electrolyte imbalances, fluid loss, visible peristalsis, vomiting
What is peritonitis?Inflammation of the peritoneum related to pathogenic (like bacteria) or chemical invasion into the peritoneal cavity
What are manifestations of peritonitis?Board-like rigid abdomen, fever, elevated WBCs, large amount of ECF, increased pain with movement, shallow breathing
A person with an immune reaction (allergy) to gluten is said to have?Celiac Sprue (celiac disease)
Hepatitis B is transmitted by?Blood, booty (sex), and baby (perinatally)
Hepatitis C is transmitted by?Blood (like in IV drug use, infusions), and sex
Which types of hepatitis are transmitted by the fecal-oral route?A and E
Which hepatitis is most likely to cause cirrhosis?Hepatitis C
What is the first symptom of colorectal cancer?Usually bleeding
What laboratory tests indicated hepatobiliary function? And which of these is the most specific to the liver?ALT (most liver specific), AST, ALKPHOS, NH3, Bilirubin, Coagulation panels (PT, INR), Albumin
Which type of bilirubin causes jaundice?Unconjugated
What are some common manifestations of Cirrhosis?Hepatomegaly, jaundice, weakness, weight loss, diarrhea, abdominal pain, anorexia
What are the LATE manifestations of Cirrhosis?Bleeding, Varices, Hepatic encephalopathy, Splenomegaly, Thrombocytopenia, Gynecomastia
Hepatocellular carcinoma arises from?Liver cells
Cholangiocarcinoma arises from?Bile ducts
Differentiate the pain between cholecystitis and cholelithiasis?"Cystitis" - RUQ or epigastric pain; "Lithiasis"- RUQ, epigastric with radiation to back, right shoulder and right scapula
In acute pancreatitis what laboratory findings would you expect?Increased amylase and lipase, increased bilirubin, increased WBC, and increase blood glucose (hyperglycemia)
Why would a patient with acute pancreatitis have elevated blood glucose?If the pancreas is autodigesting itself then insulin is not be secreted
What type of pain would you expect in acute pancreatitis?Mild to severe epigastric/ abdominal pain radiating to back, increased pain when lying flat
Pancreatic cancer painDull epigastric pain that worsens after eating



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