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Chapter 11 - How Genes Are Controlled

AB
Cloneproduced by asexual reproduction and is genetically identical to its parent
Gene Expressionthe overall process of information flow from genes to proteins
Promotersequence where RNA polymerase binds
Operatoris where a repressor can bind and block RNA polymerase action
Operona group of genes under coordinated control in bacteria
Repressora protein that blocks the transcription of a gene or operon
Regulatory Genecodes for a repressor protein
Activatorsenhance RNA polymerase binding to the promoter
Differentiationinvolves cell specialization, in both structure and function
Histonesa small protein molecule associated with DNA and important in DNA packing in the eukaryotic chromosome
Nucleosomeare formed when DNA is wrapped around histone proteins
X Chromosome InactivationIn female mammals, one of the two X chromosomes is highly compacted and transcriptionally inactive
Barr BodyInactivated X chromosome
Transcription Factorspromote RNA polymerase binding to the promoter
Enhancersa eukaryotic DNA sequence that helps stimulate the transcription of a gene at some distance from it.
Silencersare repressors that inhibit transcription
Alternative RNA SplicingProduction of different mRNAs from the same transcript
RNA Interference (RNAi)Prevents expression of a gene by interfering with translation of its RNA product
Homeotic Geneare master control genes that determine the anatomy of the body, specifying structures that will develop in each segment
DNA MicroarrayContains DNA sequences arranged on a grid
Signal Transduction Pathwayis a series of molecular changes that converts a signal at the cell’s surface to a response within the cell
RegenerationRemaining cells divide to form replacement structures
Nuclear TransplantationReplacing the nucleus of an egg cell or zygote with a nucleus from an adult somatic cell
Reproductive CloningImplant embryo in surrogate mother for development...new animal is genetically identical to nuclear donor
Embryonic Stem (ES) CellsA cell in the early animal embryo that differentiates during development to give rise to all the different kinds of specialized cells in the body.
Therapeutic Cloningcan produce stem cells with great medical potential
Adult Stem Cellscan give rise to many but not all types of cells
Oncogenea cancer-causing gene; usually contributes to malignancy by abnormally enhancing the amount or activity of a growth factor made by the cell
Proto-oncogenenormally promote cell division
Tumor-suppressor GenesNormally inhibit cell division
Carcinogensare cancer-causing agents that damage DNA and promote cell division


Biology Teacher
Eastlake High School

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