| A | B |
| Abolitionist | Northerners that want to rid the country of slavery |
| Secede | To break away from an organization, government or alliance |
| Compromise | An agreement or solution to a dispute |
| Popular Sovereignty | The idea that the government's authority comes from the people, people vote to decide issues and laws |
| Sectionalism | Loyalty to one's region or state before the country |
| Republican Party | Party established in 1854 with the goal to rid the country of slavery |
| Missouri Compromise | 1820 agreement that made Missouri a slave state, Maine a free state, and slavery could not exist above the 36 30 latitude. |
| Wilmot Proviso | Failed attempt to prevent slavery from spreading to new territories. |
| Compromise of 1850 | Agreement that made California a free state, New Mexico and Utah could decide on slavery, slave trade is outlawed in Washington DC, and passed the Fugitive Slave Law |
| Fugitive Slave Law | Legislation that would make it easier to find and capture slaves |
| Uncle Tom's Cabin | Fictional novel written by Harriet Beecher Stowe that portrayed slavery. |