| A | B |
| Columbian Exchange | the interchange of plants, animals and diseases between the Old World and the Americas following Columbus’s arrival in the Caribbean |
| Balance of Trade | the difference in value between the total exports and total imports of a nation |
| Mercantilism | an economic system to increase a nation’s wealthy by government regulation of all the nation’s commercial interests |
| Capitalism | an economic system where businesses are privately owned by individuals or groups of individuals |
| Encomienda System | system under which a Spanish soldier was granted a tract of land with its Indian inhabitants |
| Commerce | another word for trade |
| colony | a body of people who settle far from home but maintain ties with their homeland |
| conquistadors | Spanish conquerors |
| exploration | to travel for the purpose of discovery |
| circumnavigate | to sail around the world |
| immunity | the body’s ability to protect itself against certain diseases |
| smallpox | a very serious and contagious disease that was introduced to the New World by explorers |
| epidemic | an outbreak of contagious disease that spreads rapidly and widely |
| Middle Passage | the voyage that brought captured Africans to the Americas |
| Triangle Trade | trade occurring between England, Africa and the Americas |