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Cell Cycle, Mitosis, and Cell Differentiation

Vocabulary terms from Chapter 5 on the cell cycle, mitosis, and cell differentiation

AB
Gap1 (G1)1st stage of cell cycle: Cells grow, carry out normal functions, and replicate their organelles
Synthesis (S)2nd stage: DNA replication duplicates chromosomes, resulting in two identical copies (sister chromatids)
Gap 2 (G2)3rd stage: additional growth, duplication of centrioles (centrosomes)
Mitosis (M)4th stage of cell cycle: division of nucleus and contents (mitosis) and division of cytoplasm (cytokinesis)
mitosisdivision of the nucleus and its contents (divided into 4 phases)
cytokinesisdivision of the cytoplasm, producing 2 daughter cells
chromosomeone long continues thread of DNA that consists of numerous genes along with regulatory information
histonespositively charged proteins that DNA wraps around, forming chromatin
chromatinthe loose combination of DNA and proteins in interphase, when the cell is not actively dividing
chromatidone half of a duplicated chromosome (sister chromatids)
prophasechromatin condenses to form chromosomes, the nuclear envelope breaks down, centrioles begin to move to opposite poles, spindle fibers form
metaphasespindle fibers attach to each chromosome and chromosomes are aligned along the equator
anaphasechromatids separate and move to opposite sides of the cell
telophasechromosomes begin to decondense, nuclear membranes start to reform, spindle fibers disappear
interphasethe cell copies its DNA and grows in preparation for division
apoptosisprogrammed cell death, used during development to shape tissues and during cell cycle regulation to prevent damaged cells from dividing
canceruncontrolled cell growth
cancer cellscome from normal cells that have suffered damage to the genes that help make proteins involved in cell-cycle regulation
asexual reproductioncreation of offspring from a single parent that does not involve the joining of gametes
cell differentiationprocess by which unspecialized cells develop their mature forms and functions by having different proteins (gene expression)
stem cellsa unique type of body cell that have 1) the ability to divide and renew themselves for long periods of time, 2) remain undifferentiated in form, and 3) develop into a variety of specialized cell types
adult stem cellspartially undifferentiated cells (multipotent) that can be treated with the right combination of molecules to produce a completely different type of tissue
embryonic stem cellscome from donated embryos, are pluripotent and can form any of the body cell types
1st stage of mitosis, prophase
2nd stage of mitosis, metaphase
3rd stage of mitosis, anaphase
final stage of mitosis, telophase
Gap 0 (G0)cells have left the cell cycle, are not dividing but are metabolically active


High School Science Teacher
Benedictine High School
Cleveland, OH

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