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Biochemistry Chapter 7 Amines/Amides

AB
Amidesproducts of the amidation reactions; functional group-the hydroxyl group of a carboxyl group is replaced by a nitrogen group
naming amidesdropping the ic acid (oic acid ) from the carboxylic acids names and adding the suffix amide
Amides are ______ except formamide which is a liquidsolid
Aminescontain 1 or more organic groups bonded to N-atom in compounds
primary amine1 carbon atom is bonded to a N atom
secondary amine2 carbon atom is bonded to a N atom
tertiary3 carbon atom is bonded to a N atom
naming aminesthe alkyl groups bonded to the N-atom are listed in alphabetical order; prefixes di - and tri – are used for 2 or 3 identical substituents
aromatic aminesuse the name analine
naming aromatic aminesAlkyl groups attached to the N of aniline are named with the prefix N-followed by the alkyl name
Physical properties of amines, methyl, dimethyl, trimethyl and ethylamine are ______gases
Amines solubility in H20 (HOH)1 - 6 atoms are soluble; 7 or more are not soluble
Amine boiling pointslower than alcohol because polarity of (-NH) is lower than (-OH)
amines react as _______ basesweak
amidationamines react with carboxylic acid to form an amide
Amides with _____ are soluble in H20 (HOH)1-5 carbons
in Hydrolysis, ______ is added to an amide to split the moleculeH20 (HOH)
products of hydrolysis of an amide are ______amine and carboxylic acid
Function of dopaminecontrols muscle movement, regulates sleep/wake cycle; improves cognition, attention, memory, learning
Function of histaminecauses allergic reactions, inflammation, watery eyes, itching skin, hay fever, closure of throat in shellfish allergies
Alkaloidsphysiologic nitrogen containing compounds produced by plants, examples, nicotine, caffeine, morphine, etc
Ammonia salts are _____ at room temperature and ______ in H20solid; soluble
Naming salts of amines ______________is replaced with "amide"the "oic acid" or "ic acid" in the correspnding carboxylic acid name



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