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HM CH.1 ENDOCRINE SYSTEM

endocrine system

AB
endocrine system sends messages byway of chemical messengers called hormones
hormonessecreted from endocrine gland cells into theblood and distributed by the circulatory system
endocrine glandssecrete hormones directly into the blood, because they have no duct system
glands of the system are often calledductless glands
cells that are affected by the hormone are referred to astarget organ cells
hormone producing glands includehypothalamus, pituitary, thyroid, parathyroids, adrenals, pancreas, gonads
hypothalamusstructure in the brain, synthesizes chemicals that are secreted to the pituitary gland to stimulate the release of its hormones and to help regulate body temperature
pituitary glandsmall, pea-sized at the base of the brain in the sella trucica, saddle-shape depression of the shenoid bone
master gland of the bodythe pituitary gland is known as
pituitary gland consist of two separate glands known asanterior and posterior pituitary gland
anterior pituitary gland important role ininfluencing body functions
somatotropinthe growth hormone
overproduction of somatotropin causesgiantism
lack of somatotropin causesdwarfism
an overporduction of somatotropin after the growth years causesacromeagly, characterized by abnormally large hands, feet and jaw
thyrotropin, thyroid-stimulating hormoneinfluences the growth, development, and secreting activities of the thyroid gland
gonadotropininfluences the gonads and is essential for normal develpment and functioning of both male and female reproductive systems
adrenocorticotropin hormoneacts primarily onadrenal cortex, stimulating its growth and its secretion of corticosteroids.
corticosteroids hormoneaffect every cell in the body and are discussed in more detail later in this section
poosterior pituitary gland has two hormonesantidiuretic and oxytocin hormones
andidiuretic hormonepromotes conservation of water by the kidneys
diabetes insipiduswhen antidiuretic hormone is not produced in adequate amount , the daily urine volume is between 10 and 15 liters instead of the normal 1.5 liters
oxytocin stimulatescontracion of the muscles of the uterus, particularly during pregnancy, important in production of milk in the mamary glands
thyroid gland shapebutterly
thyroid gland locatedanterior part of the neck, below the larynx
thyroid gland consists of how many lobestwo lobes, one on each side of the upper trachea, connected by a strip of tissue called isthmus
thyroid secretesiodine containing hormone thyroxin, controls the rate of cell metabolism
hyperthyroidismexcessive secretion of thyroxin raises the metabolic rate
hyperthyroidism characterized byfast pulse rate, dizziness, increased basal metabolism, profuse sweating, tremors, nervousness, and tremendous appetite coupled with a loss of weight
simple goiterdiffuse and painless enlargement of the thyroid gland, enlarges to compensate for the lack of iodine
hypothyroidisminsufficient secretion of thyroxin
in hypothyroidism pt exhibitsdecrease in basal metabolism, and sweating is almost absent, weight gain, sonstant fatigue, heart rate slow, simple goiter may fom, personality changess, slow lethargic mental functioning
hypothyroidism during childhood can lead tocretinism, condition characterized by retarded mental and physical development
parathyroid glands four small round bodyies locatedposterior to the thyroid gland
parathyroid glands produceparathormone hormone, regulates the calcium and phosphorus content of the blood and bones
diminished function or removal of parathyroid glands results ina low calcium level in the blood, extreme cases death may occur preceded by strong contraction of the muscles and convulsions
hyperparathyroidismparathyroid homone in the blood, causes calcium levels in the blood to become elevated by the withdrawal of calcium from the bones, leaving the skeleton demineralized and subject to spontaneous fractues
in hyperparathyroidism theexcess calcium may be deposited asstones in the kidneys
adrenal glands located onsuperior surface ofeach kidney, fitting like a cap
adrenal gland outer portion and inner portion are known ascortex, and medulla
adrenal cortexproduce three types of steroid hormones, mineralocorticoids, glucocorticoids, androgens and estrogens
mineralocorticoidsregulators of fluid and electrolyte balance. AKA salt and water hormones
glucocorticoidsessential to metabolism, increase certain liver functions have anti-inflammatory effect
androgens and estrogenssex hormones, male androgens, female estrogens
adrenal medulla secretesepinephrine adrenalin
heart rate, respiration rate and depth, blood pressure, blood sugar levels, and metabolism are all increased byepinephrine
norpinephrineproduced in adrenal medulla, chemical precursor to epinephrine
pancreastwo types of secretory tissues, first secretes digestive juice through a duct to the small intestine, while the other tissue releases hormones into body fluids
the endocrine portion of the pancreasconsist of celss arranged in groups called the island (islets) of langerhans
the islands of langerhans contain three types of endocrine cellsalpha, beta, and delta
alpha cellssecrete the hormone glucagon
glucagontemporary rise in blood sugar levels
beta cellssecrete insulin, which is essential for carbohydrate metabloism
insulinlowers blood sugar levels by increasing tissue utilization of glucose and stimulating the formation and storage of glycogen in the liver
delta cellsproduce the hormone somatostatin
somatostatinhelps regulate carbohydrates by inhibiting the secretion of glucagon
diabetes mellitusislet cells are destroyed or stop functioning, the sugar absorbed from the intestine remians inthe blood and excess sugar is excreted by the kidneys into the urine
gonadssex organs of the reproductive system
testesmale gonads, produce male hormone testosterone
accessory sex organsinternal and external sex organs for males
male secondary sex characteristicshair growht on face, chest, axillary, and pubic region, elargement of larynx, (adam's apple), lower-pitched voice, thickening of the skin, increased muscle growth, broadening of shoudler and narrowing of waist, thickening and strengthening of bones
female gonadsovaries, produce estrogen and progesterone
estrogenmaintenance of female accessory sex organs and secondary sex characteristics, changes mucous lining of uterus during mensturation
progesteroneprepares uterus for reception and development of the fertilized ovum and maintains the lining during pregnancy
female secondary sex characteristicsdevelpment of breast, mammary glands, increased quantities of fatty tissue in breasts, thighs, and buttocks, increased vascularization of the skin


HM3 Bushong

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