| A | B |
| Aunt Betty | She has numerous miscarriages because she works too hard and eventually dies from working too hard. |
| Daniel Jacobs | He is Harriet's father, a carpenter, who dies. |
| Elizabeth Horniblow | She is the original owner of Harriet and her whole family. |
| Jenny | Young curious girl who causes Harriet to leave the widow's house and Gran's attic. |
| John Jacobs | Harriet's brother who escapes to North and eventually goes to college and works on a whaling ship. |
| Joseph Jacobs | Harriet's son; figures out where she is hiding and keeps watch. |
| Louisa Jacobs | Harriet's daughter |
| Martha Blount | White woman, hides Harriet when Harriet first runs away from Dr. Norcom. |
| Maria Norcom | The perfect picture of meanness, yet she attempts to protect Harriet from her husband. |
| Mary Matilda | Infant child whom Harriet is employed to watch/raise and who later chases Harriet in NY City to try to get her back. |
| Molly Horniblow | Hides Harriet in her garret for 7 years. |
| Dr. Norcom | Makes sexual advances toward Harriet. |
| Robert | Harriet's first true love; he is free born and moves south |
| Samuel Sawyer | The father of Harriet's children. |
| Sarah | The woman Harriet hides with in a ship's hold and escapes with by sailing North. |
| Uncle Stephen | A sailor, he is Betty's husband, who escapes to the North. |
| Mrs. Willis | She buys Harriet's freedom from the Norcoms for 300 dollars. |