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Inflammation Content Review

AB
Antacids - Take when?Give 1 hour after meals. Take with a full glass of water.
H2 Blockers - Take when?Give with or before meals.
PPI’s - Take when?Give before the first meal of the day.
H Pylori Triple Therapy-cillin + -mycin + PPI (-azole)
Examples: Pepcid, TagametHistamine 2 Blocker (H2 Blocker)
Examples: Omeprazole, pantoprazole, others ending in -prazoleProton Pump Inhibitors (PPIs)
Rule of Admin for Multiple GI Meds PrescribedGive them one hour apart from each other
Stops Nausea & VomitingZofran (Ondansetron) Compazine/Promethazine
Stops DiarrheaLomotil or Imodium
Antidiarrheal MedicationsCaution over use (r/t toxicity); watch for constipation
Slows/Inhibits/Stops Stomach AcidAntacids, H2 Blockers, PPI’s
Sucralfate/CarafateProtects mucosal lining of the stomach
Sucralfate/Carafate - Take when/how?Give PO and take on an empty stomach. Do not give with Coumadin or Dilantin
Examples: Maalox, Tums, Milk of magnesiaAntacids
NSAIDs TeachingTake with full glass of water or milk or with food. Avoid alcohol!
Hold NSAIDs how long before surgical procedures?No less than 1 week
NSAIDs increase bleeding potential (why)?Because they inhibit platelet aggregation
CorticosteroidsMainstay Drug Tx IBD Exacerbations
Examples: Dexamethasone, cortisone, prednisone, -oneCorticosteroids
Corticosteroids TeachingTake exactly as prescribed, gradually decrease use, never abruptly stop
What must be monitored taking a steroid?Potassium level, glucose level, and I&O
Corticosteroids may cause symptoms of...Cushing’s Syndrome
Corticosteroids will delay...Wound Healing
Yes in PO for surgery should you still get the steroidYes, due to excess inflammation r/t surgery, stress, and illness.
UC signs, symptoms, complaintsAbdominal pain, bloody diarrhea (>20 stools/day), N&V, weight loss
UC appropriate dietLow fiber, AVOID fiber, fatty/greasy foods to decrease diarrhea. Avoid alcohol and caffeine. Increase fluid intake.
UC TreatmentsNPO, corticosteroids and or removal of colon and rectum (will need ileostomy)
Corticosteroid CautionAvoid exposure to infection, live vaccines, immunizations
Duodenal Ulcer PainOccurs on empty stomach; subsides with food; feed a duodenal ulcer
Gastric Ulcer PainOccurs with meals or after eating; starve a gastric ulcer
PUD teachingAvoid Smoking, Alcohol; Manage Stress
PUD ComplicationsHemorrhage, Perforation, Peritonitis
PUD PeritonitisRigid, board-like abd, severe pain, decreased to hypo vowel sound! Get VS, check and/bs, Call Rapid!
Crohn’s location/characteristicsAnywhere from mouth to anus; cobblestone pattern
IBD Foods to AVOIDDairy products and high fiber foods will increase diarrhea
Excess Diarrhea Electrolyte Concern?Hypokalemia
Crohn’s TxCorticosteroids, NPO, stress Mgmt, surgery WILL NOT help
IBD PrognosisLifelong + unpredictable s&s; Crohn’s has no cure; sometimes surgery can cure UC
PUD 1st s&sIs often serious GI bleeding
PUD vomit and still characteristics?Vomit = coffee ground; Stool = Black Tarry (melena)
Bacteria that causes most PUD?H pylori
H Pylori transmissionPoop to soup
How is bowel rest achieved?NPO and of NG to suction (stomach decompression)
Excessive DiarrheaPeri-anal skin integrity; gentle cleansing; mild soaps; protective ointment; no harsh temps or chemicals
IBD Monitor LabsCBC/RBC/H&H; values will be lower with UC due to more blood loss
GuaiacTest for Occult Blood
IBD Patient teachingMonitor report bloody stools; Stress Mgmt
Gallbladder Risk Factors (some not all)F’s: female, fluffy, forties, fertile, fatty foods familial; S = sedentary
Cholelithiasis S&S3-6 hrs post fatty meal or when pt lays down; Biliary colic r/t stone; tachycardia, diaphoresis, prostration, excruciating pain RUQ
Cholelithiasis ComplicationBiliary Obstruction = Emergency
Biliary Obstruction S&Spasty, clay colored stools
Biliary Obstruction not resolved may lead toBile Peritonitis
Cholecystitis labsLeukocytes + fever
Cholecystitis and Cholelithiasis PriorityPain Management (Opioids + NSAIDs) Infection Control, ABT prn, and fluid/electrolyte balance
Cholelithiasis Mainstay TxCholecystectomy
Cholelithiasis conservative tx/medsCholesterol solvents (dissolve stones)
AnticholinergicsDecrease secretion and counteract smooth muscle spasms in the gut
Cholecystitis/Lithiasis N&VNG Tube; gastric decompression
Examples: -diol; ursodiol, chenodiolCholesterol solvents (gall stones)


Tina Coker-Boyd

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