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Tumor Marker Flash Cards

AB
Alpha-fetoprotein (AFP)Secreted in the serum of people with hepatocarcinoma, enodermal sinus tumors, etc...Normally synthesized by the fetal liver and yolk sac.
CA 125Ovarian carcinoma
CA 15-3Monitor patients after a masetecgtomy
CA 19-9Elevated levels have been found in patients with pancreatic, hepatobiliary, colorectal, gastric, hepatocellular and breast cancers.
Carcionembryonic Antigen (CEA)Limited diagnostic value-monitor patients with diagnosed cancer
Prostate-Specific Antigen (PSA)PSA blood leveles are increased when normal glandular structure is disrupted by tumor inflammation -used as a screening test for prostate cancer
Benign tumorsGrow slowly, usually encapsulated and non-spreading
Malignant tumorsUsually invade tissues, often re-occur
Benign tumorsHave minimal mitotic activity
Malignant tumorsIncreased number of cells that accumulate
Beta-2-microglobulinmultiple myeloma
HCG - malestesticular cancer
Beta-2-microglobulinLeukemia
Translocation of Chromosome 9/22BCR/ABL transfusion gene



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