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5. T3 CVS Pathologies- Review

AB
Congenital heart diseaseCyanotic [right to left shunt] vs acyanotic [left to right shunt]
Acyanotic congenital heart diseaseVentricular and Atrial Septal Defects and Patent Ductus Arteriosus
Ventricular Septal DefectMost common congenital defect; more common in Down’s syndrome
Atrial Septal DefectSecond most common congenital heart disease; loud P2 heart sound
Patent Ductus ArteriosusFailure of ductus to close after birth
Cyanotic congenital heart diseaseFallot’s tetralogy
Fallot’s tetralogyMost common cyanotic congenital heart disease
Features of Fallot’s tetralogyPulmonary stenosis
Transposition of the great vesselsRare cyanotic congenital heart disease
Persistent Truncus ArteriosusRare cyanotic congenital heart disease
Rheumatic fever Post-strep complication:Jones’ major and minor criteria + raised ASOT
Jones’ major criteriaSydenham chorea
Jones’ minor criteriaPolyarthralgia
Type of erythema in rheumatic feverErythema marginatum: red rash with a serpiginous [snake-like] border
Jones’ minor criteriaFever
Anti-Streptolysin O TiterAnti-Streptolysin O antibodies; Type II hypersensitivity; recent strep infection
Rheumatic fever pathologyAschoff bodies and MacCallum’s patches in the left atrium
Rheumatic Valvular Heart DiseasePersistent damage to the mitral and then aortic valves
Subacute endocarditisInfection of previously damaged valves with Strep viridans
Features of subacute endocarditisLow grade fever
Acute bacterial endocarditisInfection of normal valves with Staph aureus; high fever
Libman Sacks EndocarditisVerrucous endocarditis caused by Systemic Lupus Erythematosus
Coronary Artery Disease aka Ischemic Heart Disease:angina pectoris and myocardial infarction
Prinzmetal anginaCoronary artery spasm
Myocardial infarctionSqueezing chest pain with sweating
ECG changes in MIST elevation
Congestive heart failureCAD
Left [forward] heart failureDilated left ventricle
Right [backwards] heart failureLeft heart failure
Most common cause of RHFLeft heart failure
Cor pulmonaleRight-sided heart failure due to chronic lung disease like COPD
PericarditisInflammation of the pericardium: viral
Bread and butter appearanceFibrinous exudate seen in rheumatic fever pericarditis
Cardiomyopathy Damage to the myocardium:viral infection
Types of cardiomyopathiesDilated
Dilated cardiomyopathyMost common type of cardiomyopathy
Restrictive cardiomyopathyAmyloidosis is the most common cause
Hypertrophic cardiomyopathyCommon cause of sudden death in young adults
Stress-related cardiomyopathyBroken heart syndrome aka Takotsubo cardiomyopathy
Subclavian steal syndromeNarrowing of one subclavian artery; reversed flow in the vertebral artery
Coarctation of the aortaNarrowed aortic arch-radio-femoral delay-upper limb hypertension
Site of coarctationPost-ductal is more common than pre-ductal narrowing
Abdominal Aortic aneurysmOlder male smokers
Atherosclerosis Cause ofcoronary artery disease CVAs and some aneurysms
Foam cellsCharacteristic feature of atherosclerosis aka lipid-filled macrophages
Takayasu diseaseGranulomatous inflammatory autoimmune: pulseless disease
Buerger’s diseaseThromboangiitis obliterans; young male smokers; pallor on elevation of legs
Polyarteritis NodosaSegmental autoimmune inflammation of medium size arteries; Hepatitis B
Atrial myxomaBenign connective tissue tumor seen more commonly in the left atrium


PCCF
FL

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