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11. T3 Resp. Pathologies- Review

AB
AsthmaReversible bronchospasm; Charcot Leyden’s crystals
AtelectasisPartial collapse of the lung: compression
Compression atelectasisPleural effusion or pneumothorax: pushes trachea away from side of lesion
Contraction atelectasisScarring due to tuberculosis; pull trachea towards side with pathology
Resorption atelectasisForeign body blocking bronchus; pulls trachea towards side with pathology
COPDChronic Obstructive Pulmonary Disease: emphysema and chronic bronchitis
EmphysemaPink puffers with pursed lips breathing; overinflated lungs
Types of lung damage in emphysemaCentriacinar and panacinar α1-anti-trypsin deficiency
Centriacinar type of emphysemaAssociated with cigarette smoking
Panacinar type of emphysemaAssociated with α1-anti-trypsin deficiency
Chronic bronchitisBlue bloater; cough >3/12 for 2 consecutive years
Lung cancerWeight loss
Lung cancer typesSquamous cell [35%]
Squamous cell lung cancerMost common cancer seen in patients with asbestosis and smoking
Causes of lung cancerSmoking
Lung cancer presentationCough
Small cell lung cancerAssociated with ectopic PTH
Pancoast tumorApical lung cancer may present with hoarseness and Horner’s syndrome
HoarsenessDamage to the recurrent laryngeal nerve
Horner’s syndromeUnilateral ptosis
Weakness in the handInvasion of the lower roots of the brachial plexus
PneumoconiosisOccupational lung disease due to inhalation of inorganic material
AnthracosisCoal miners; inhalation of anthracite; not associated with lung cancer
AsbestosisAsbestos used in fire proofing
SilicosisStone quarry workers; inhalation of silica dust; most common worldwide
SiderosisIron ore workers; inhalation of iron oxide dust
Caplan’s lungPneumoconiosis [mainly anthracosis] seen in rheumatoid arthritis
Hypersensitivity lung diseasesType IV hypersensitivity reaction due to inhalation of organic material
BagassosisSugar cane workers; exposure to sugar cane waste
ByssinosisCotton millers; cotton or flax textile fiber dust inhalation
Farmer’s lungFarmers exposed to hay dust or moldy hay
Silo filler’s lungChemical pneumonitis due to exposure to nitrogen dioxide in silos
Bird fancier’s diseaseType 1 hypersensitivity lung disease caused by inhaling dry bird poop
PneumoniaLung infection with congestion
Pleural effusionExcess fluid in pleural cavity: CHF
TuberculosisCaseous necrosis
Ghon focusSubpleural focus of calcified necrosis in lower part of the upper lobe
Ghon complexGhon focus PLUS reactive regional lymphadenopathy
Primary tuberculosisMost common in children with Ghon focus and reginal nodes
Secondary tuberculosisReactivation of quiescent primary tuberculosis due to immune suppression
SarcoidosisBlack females
Other features in sarcoidosisIritis
Erythema nodosumRed


PCCF
FL

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