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Week 6 - Drugs in Increased ICP
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| A | B |
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| Mannitol IV | Osmotic diuretic |
| IV 0.9% sodium chloride | Preferred IV solution |
| 5% dextrose in water or 0.45% sodium chloride | serum osmolarity decreases, which causes cerebral edema |
| Phenytoin [Dilantin] | Antiseizure drugs |
| Corticosteroids (dexamethasone) | Used in brain edema, bacterial meningitis |
| Histamine (H2)-receptor antagonist | Cimetidine, ranitidine |
| Proton pump inhibitor | Pantoprazole (Portonix) |
| Barbiturates | Pentobarbital, thiopental |
| Propofol (Diprivan) | No Analgesic effect |
| coughing, straining should be avoided | To prevent increasing ICP |
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