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IMM-Miller 5th ed Ch 4.3

AB
T-dependent antigensAn antigen that requires T-cell help in order for B cells to respond.
T-independent antigensAntigens that are able to elicit antibody formation in the absence of T cells.
Clonal expansionProliferation of lymphocytes during an immune response to create a population of identical cells, all capable of responding to the same antigen.
ChemokinesA large family of homologous cytokines that promote migration of white blood cells through chemotaxis.
Effector cellsMature, functional T lymphocytes or B lymphocytes that carry out the functions of immune responses.
Central toleranceDestruction of potentially self-reactive T and B cells as they mature in either the thymus or the bone marrow.
ChemotaxinA protein or other substance that acts as a chemical messenger to produce chemotaxis.
MHC restrictionThe selection of thymocytes that will only interact with the major histocompatibility complex (MHC) antigens found on host cells.



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