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module 1, kidney theory

rise 1050: transport mechanisms
rise 1052: Normal kidney function vs HD
rise1053: endocrine functions of the kidneys vs HD
rise 1054: characteristics of CKD

rise 1055: manifestations of CKD
rise 1056: left ventricular hypertrophy and pericarditis
rise 1058 anemia in ckd
rise 1059: systemic effects, CKD and mineral bone disorder
rise 1060: AKI vs CKD

AB
what are the 4 transport mechanismsconvection, diffusion, osmosis, ultrafiltration
ultrafiltrationparticles pushed through a SPM
diffusionparticles moves from high to low
osmosisfluid moves from an area of low to high
convectionsolutes dragged across SPM along with fluid
what are the kidneys exceretory functions1. normalize electrolytes 2. remove wastes 3. provide fluid and acid base balance
how do we replace normal excretory functions?1. by normalizing electrolytes through the use of acid concentrate 2. providing fluid balance through ultrafiltration
what is the function of acid concentrateprovides the concentration gradient for diffusion to take place and helps normalize electrolytes
what is the function of bicarb in the dialysate solution?buffers the acid concentrate
what is the function of bicarb when it diffuses into the patients bloodnormalizes body pH
hyperKALMIA name 4 s/s5.5, extreme muscle weakness, abnormal heart rhythm, possible cardiac arrest
HYPOkalemia name 8 s/s3.5, fatigue, muscle weakness, paralysis, respiratory failure, cardiac instability, arrhythmias, cardiac arrest
what is the normal body pH7.35 to 7.45
what are the 3 kidney endocrine functions1. renin secretion 2. erythropoietin secretion 3. vitamin d activation
how do we replace normal endocrine kidney functions?provide meds
how much of the normal kidney function is replaced by HD15%
what is uremia and how does it affect the bodybuildup of wastes in the blood d/t kidney failure and affects all body systems
what are the 3 most common causes of CKD1. diabetes, 2. hypertension 3. polycystic kidney disease
name 6 treatment goals1. controlling symptoms 2. encourage pts to participate in their healthcare 3. kidney replacement therapy modality education 4. managing comorbidities and complications 5. minimize effects of ckd on lifestyle 6. slow progression of ckd
why is it important to know what caused your patients ckdthe nurse and pct can inquire about possible problems during data collection and assessment
name 3 s/sx of fluid imbalance1. hypertension 2. SOB 3. edema
why is sodium balance important1. volume expansion 2. increased cardiac output 3. increased peripheral vascular resistance 4. increased blood pressure
name systemtic effects of CKD1. dry, itchy skin 2. peripheral neuropathy 3. GI problems 4. physological problems
what to do for dry, itchy skinuse hyperfatted soaps and lotions
what to do for peripheral neuropathymonitor for decreased motor function, decreased strength in legs, RLS, burning feet, do not walk barefoot, have good foot care practices
what to do for GI problemsinform RN and MD for any bleeding problems, constipation, diarrhea, ER visits, take meds as ordered, stool softeners
what to do for psychological problemsverbalize struggles to IDT (core team) especially the social worker
what is the consequence of prolonged fluid overload and hypertensionleft ventricular hypertrophy
what is pericarditisinflammation of the membrane (pericardial sac) surrounding the heart
what is the tx for pericarditisdecrease or stop heparin, more frequent dialysis
what is a common cause of hypertension in dialysis patientsfluid overload
left ventricular hypertrophy leads to?1. ischemic heart disease 2. arrhythmia 3. myocardial infarction 4. sudden death
why are pts with CKD anemicRBCs only have a life span of 60 days instead of 120 days
name primary cause of anemialack of the hormone erythropoietin (EPO
name secondary cause of anemiainadequate iron stores, inadequate dialysis, malnutrition, blood loss during treatment
what can you do to avoid contributing to lower hemoglobin and blood loss in dialysis patientsverify correct erythropoietin stimulating agent (ESA) dose is adminstered, rince back until venous line is pink tingeed, and avoid repeat lab draws
what are the 4 key elements contributing to CKD-Mineral bone disorder (MBD)?1. calcium 2. phosphorous, 3. PTH 4. Vitamin D (Calcitriol) they all lead to CKD_MBD when they are abnormal
what are the s/sx of CKD-MBD in addition to bone-disease?soft tissue calcification, itching, muscle weakness, pathological fractures, tendon ruptures, compression of vertebre, atherosclerosis, heart disease
what is RN role in CKD-MBD managementreport s/sx, urge pts to take meds, report problems related to non-compliance
define the term AKIwide spectrum of kidney issues, acute kidney failure, less catastrophic kidney function changes, may dialyze in an outpatient facility until kidney function recovers
give 3 examples of pre renal causes of AKIobstruction, volume depletion, impaired cardiac function, decreased cardiac output
give 3 examples of intra renal causesischemic ATN, sepsis, acute interstitial nephritis, septic shock, anaphylaxis, drugs, goodpasture syndrome, acute glomerulonephritis, trauma, open heart surgery
give 3 examples of post renal causesobstruction, bladder rupture, pregnancy
what is the difference between AKI and CKDwith AKI if you eliminate the cause, it can lead to return of kidney function
what is the difference between CKD and AKIyou cant elimiate the cause of CKD like diabetes, HTN, genetic disorders (PKD)
how do you help in restoring AKI kidney functionfind the cause of the AKI
what do you need to consider in regard to their vascular accesspatients will typically have a dialysis catheter, be careful to avoid catheter related infections
how do you protect the kidneys from futher injuryavoid substances to the kidney which may be toxic (radiology contrast), amphotericin B, low dose aspirin, NSAIDS)
what is important when monitoring weight and bp with AKIkeep a little extra fluid on the patient so it is available to the kidneys when they start filtering/ultra-filtering on their own
AKI patients are at increased risk for which complications?hypovolemia and hypotension



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