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ClnPth1 Module 8 Unit 2 Review

AB
CancerGroup of diseases in which abnormal cells grow uncontrollably and crowd out normal cells.
CarcinogenesisBeginning or development of cancer due to changes in cellular DNA
DysplasiaAbnormal, precancerous cell growth
Tumour (Neoplasm)Mass of abnormal cells that may be benign or malignant.
Benign tumourNoncancerous tumour that grows slowly, is made of cells that remain differentiated, is encapsulated, and doesn't spread or metastasize
Malignant tumourCancerous tumour that becomes undifferentiated, is not encapsulated, invades tissues and may metastasize.
DifferentiatedCells that resemble the original tissue type.
AnaplasticUndifferentiated cells that no longer resemble the original tissue.
In SituTumour confined to its site of origin (original location).
MetastasisSpread of cancer from the primary site to another part of the body.
Cystic TumourTumour containing large fluid-filled spaces.
Fungating TumourTumour with mushroom-like growth projecting from tissue.
Inflammatory TumourTumour causing redness, swelling, and heat.
Medullary TumourLarge, soft, fleshy tumour.
Necrotic TumourTumour containing dead tissue.
Polypoid TumourTumour or growth projecting outward from a base.
Ulcerating TumourTumour type characterized by open exposed surface caused by tissue death.
Verrucous TumourTumour with a wart-like appearance
Tumour GradingClassification based on cellular differentiation and maturity.
Tumour StagingClassification based on extent of spread.
CarcinomaCancer arising from epithelial tissue.
Colorectal CancerCancer of the colon or rectum; often hereditary.
Esophageal CancerCancer of the esophagus associated with smoking, alcohol, and GERD.
Liver CancerCancer often begins in bile ducts or liver cells and is associated with hepatitis B or C
Stomach CancerCancer often associated with chronic Helicobacter pylori infection.
Breast CancerCancer arising from breast tissue, often ductal or lobular; most often detected through mammography.
Pancreatic CancerCancer difficult to detect early with poor survival rates.
Lung CancerCancer strongly associated with cigarette smoking and asbestos exposure.
Basal Cell CarcinomaSkin cancer arising from the deepest epidermal layer; presents as a small bump on sun-exposed areas.
Squamous Cell CarcinomaSkin cancer caused by UV exposure.
Malignant MelanomaAggressive skin cancer arising from malignant transformation of melanocytes; often begins as an atypical mole.
Ovarian CancerCancer of the ovary or fallopian tube, often cystic, hereditary and originates in the ovaries or fallopian tube lining.
Cervical CancerCancer strongly associated with HPV infection.
Testicular CancerCancer of the testes with good prognosis if detected early; risk increases with undescended testes.
SarcomaCancer arising from bone, muscle, or connective tissue.
OsteosarcomaMost common primary bone tumour.
LeukemiaCancer arising from hematopoietic stem cells in bone marrow.
Hodgkin LymphomaLymphoma involving Reed-Sternberg cells.
Non-Hodgkin LymphomaLarge group of malignancies developing from lymphocytes
OncologistPhysician specializing in cancer diagnosis and treatment.
CBC with differentialTest that measures immune cell activity and can show abnormal cells in the blood
Prostate-Specific Antigen test.Test used as a marker for prostate cancer
BiopsyRemoval of tissue for microscopic examination; can be incisional or excisional.
Incisional BiopsyRemoval of a small piece of a tumour.
Excisional BiopsyRemoval of an entire tumour.
Lymph Node DissectionSampling lymph nodes to assess metastatic spread.
ChemotherapyDrug treatment that damages cancer cell DNA and inhibits cell division; may also damage rapidly dividing healthy cells as a side effect
CauterizationDestruction of tissue using heat or chemicals.
CryosurgeryDestruction of tissue using extreme cold.
BrachytherapyRadiation therapy using radioactive seeds near or in a tumour.
External Beam IrradiationRadiation delivered from a machine outside the body; also called teletherapy.
ImmunotherapyTreatment using lymphocytes or monoclonal antibodies to attack cancer.
Monoclonal AntibodyLaboratory-engineered antibody used in cancer therapy.
MammogramTest commonly used to screen for breast cancer
Colonoscopyvisual examination of the colon
PET scanImaging test most sensitive for detecting metastatic cancer activity



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