| A | B |
| Gerald Ford | The only president whom two women tried to assassinate. |
| Gerald Ford | The only president to hold the office of vice-president and president without being elected to either office. |
| Richard Nixon | The only president to be elected to two terms as vice-president and two terms as president. |
| Richard Nixon | The only president to resign. |
| Lyndon Johnson | The only president sworn in on an airplane. |
| Lyndon Johnson | The only president sworn in by a woman. |
| John F. Kennedy | The only president to appoint his brother to a cabinet office. |
| Dwight Eisenhower | The only president to serve in the military in both world wars. |
| Franklin Roosevelt | Only president confined to a wheelchair. |
| William Howard Taft | The only president who had to be pried out of a bathtub so that he could make it to his inauguration. |
| Rutherford B. Hayes | The only president elected by a commision. |
| Andrew Jackson | The only president married to a pipe smoker. |
| James Monroe | The only president to run unopposed. |
| George Washington | The only president to be elected unanimously. |
| George Washington | The only president elected in an odd numbered year. |
| George Washington | The only president who did not live in Washington D. C. |
| Thomas Jefferson | The only vice-president who defeated the president he served under to become president. |
| George Washington | The only president with no political party. |
| John Adams | The only Federalist president. |
| Bill Clinton | The only president from Arkansas. |