| A | B |
| Building blocks are nucleotides | Both |
| Contains adenine | Both |
| Contains thymine | DNA only |
| Contains uracil | RNA only |
| Single strand | RNA only |
| Complementary double strands | DNA only |
| Makes up chromosomes | DNA only |
| Double helix | DNA only |
| Comes in 3 types | RNA only |
| Used at ribosomes to build proteins | RNA only (specifically mRNA) |
| In eukaryotic cells, remains in nucleus | DNA only |
| In eukaryotic cells, synthesized in nucleus and then leaves to carrry out functions | RNA only |
| Contains a 5-carbon sugar | Both |
| Contains ribose | RNA only |
| Contains deoxyribose | DNA only |
| Contains phosphate groups | Both |
| Contains cytosine | Both |
| Contains guanine | Both |
| Makes up ribosomes | RNA (rRNA) |
| Brings amino acids to ribosomes for protein synthesis | RNA (tRNA) |