| A | B |
| Europe and Asia | Two continents that are frequently combined as one land mass |
| Appalachian Mountains | oldest mountain range in North America |
| Continental Divide | Located in Rocky Mountain Region that determines what direction rivers flow |
| Canadian Shield | A horse-shoe shaped region in Northern North America |
| Great Plains | Region with grasslands that gradually increase in elevation as the region nears the Rocky Mountains |
| Coastal Range | Region with rugged mountains that are located along the Pacific Coast from California to Canada |
| Atlantic Ocean | Borders the eastern seaboard |
| Lewis and Clark | Explored the Columbia River |
| Ohio River | The "gateway to the west" |
| St. Lawrence Seaway | Links the Great Lakes to the Atlantic Ocean |
| Mississippi and Missouri Rivers | Main transportation routes for industrial and farm products |
| Sioux Indians | Lived in Great Plains |
| Kwakiutl Indians | Lived in Pacific Northwest Coast |
| Pueblo Indians | Lived in Southwest desert areas |
| Farming Techniques | English settlers learned these from Native Americans |
| Portugal | Traded in West Africa |
| LaSalle | Explored Mississippi River Valley |
| DeChamplain | founded Quebec |
| Coronado | Explored Southwest North America |
| Cabot | Explored for England |