| A | B |
|---|
| Antibiotic | microbe makes, inhibits others |
| Spectrum | range of organisms affected |
| Mode of Action | how antibiotic works |
| Selective Toxicity | toxic to microbe, not host |
| Side Effects | damage to host |
| Allergy | immune system over-reacts |
| Anaphylactic Shock | rapid drop in BP, respiratory distress |
| Superinfection | result of normal flora disruption |
| Resistant | microbe no longer sensitive |
| Plasmid | usual location of resistance genes |
| Synergism | combo of 2 or more antibiotics |
| Kirby-Bauer Test | disk diffusion for zone size |
| Zone of Inhibition | no growth around disk |
| Minimum Inhibitory Concentration | prevents visible growth |
| Penicillin | cell wall synthesis inhibitor |
| Beta Lactam | inhibits peptidoglycan formation |
| Prophylaxis | used to prevent infection |
| Cephalosporin | too broad spectrum & expensive |
| Bacitracin, Neosporin, Polymyxin | topical due to toxicity |
| Vancomycin | last resort to prevent resistance |
| Tetracycline | sun sensitivity |
| Chloramphenicol | aplastic anemia |
| Erythromycin | neonatal chlamydia in eyes |
| Rifamycin | red man syndrome |
| Ciprofloxacin | mistakenly stockpiled for anthrax |
| Sulfonamides | pneumocystis pneumonia |
| Isoniazid | synergism for TB |
| Amphotericin B | toxic antifungal |
| Nystatin | thrush |
| Tinactin | athlete's foot |
| Lamisil | fungal nails |
| Acyclovir | herpes |
| Amantadine | prophylaxis for influenza |
| AZT | AIDS |
| Chloroquine | malaria |
| Metronidazole | Trichomonas & Giardia |
| Ivermectin | heartworms & river blindness |
