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Extracellular and Intracellular Fluids

AB
The extracellular fluid includesFluids of gastrointestinal tract
the human blood volumeAbout 7% of body weight ( 5 liters)
The Hematocrit Volume equalsthe packed red cells volume
Total fluid volume is about42 liters
The ECF and plasma volumes are important in the regulation ofblood Pressure
The ECF osmolality affects the ability ofthe cell to maintain normal size
Movement of solute across a membrane occurs byDiffusion, facilitated diffusion and active transport
Movement of solvent across a membrane occurs byosmosis and Filtration
In an isotonic solutionthere is no net exchange of water
A hypertonic solution causesa cell to shrink
A hypotonic solution causesa cell to swell
Hyponatremia isbelow normal plasma Na+
Blood pressure is proportional tothe amount of water in the circulatory system
Edema isexcess water in a body region leading to swelling
High venous pressure could be associated withedema
before significant edema occur capillary pressure could be raised by17mm Hg .
The filtration coefficientIs the rate of filtration /min./mm hg/100 grams of tissue
The starling equilibrium indicatesthe near equilibrium that exists at capillary membrane
Effusionis edema formation in potential spaces
Buffers aresubstances which cushion a solution from abrupt pH changes.
Acidosis and Alkalosis occur when pH drifts away from7.4


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