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Chapter 15

AB
Computer analysis of DNA sequences is an important tool in functional genomics because it will allow researchers topredict the structure and function of gene products
most genesact in conjugtion with many other genes
PCR chain reaction requireshigh temperatures
restriction enzymes cut DNA atcertain short base sequences
point mutations on a DNA sequence is one thataffects only a single base pair
Inversion occurs whena piece of the chromosome flips 180 degrees and reattaches its self
A point mutation that results in the same protein being producedsilent mutation
Ligaseis used to connect DNA fragments
Plasmidsare used as vectors in genetic engineering
Translocation occurs whenfragments of one or two chromosomes break and bind with each other
The first single-celled eukaryotic organism to have its genome mappedS. cerevisiae
The first multicelled eukaryotic organism to have its genome mappedC. elegans
A method of producing many copies of a tiny sample of DNAPCR
A point mutation that results in the wrong protein being producedmissense mutation
A mutation that reults in NO protein or a nonfunctional protein being producednonsense mutation
The first single-celled prokaryote organisms to have its gemone mappedE. coli
RFLPrestriction fragment length polymorphisms
a mutation that changes the translation of every subsequent codonframeshift mutation
attempts to correct the genetic basis of a disordergene therapy
direct manipulation of an organism's genesgenetic engineering
the reproduction and growth of genetically identical organismscloning
A cellular process characterized by the production of multiple copies of a particular genegene amplification

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