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Extensions of Mendelian Genetics

Review of vocabulary words found in Chapter 2 of Genetics: From Genes to Genomes by Hartwell et al., McGraw-Hill.

AB
allele frequencyproportion of all copies of a gene in a population that are a given allele type
codominancewhen alleles for a gene are expressed equally
complementary gene actionwhen two genes work together to produce a particular phenotype
complementation testmethod to find out whether a phenotype is the result of mutation in one or two genes
conditional lethalan allele whose expression is fatal under certain environmental conditions
continuous traitwhen an inherited trait exhibits many intermediate forms
discontinuous traitphenotypes expressed in discrete varieties
epistasisexpression of allele of one gene masks expression of alleles of another gene
expressivitydegree to which a particular phenotype is produced by a given genotype
heterogeneous traita given phenotype is caused by mutation in one of several genes
histocompatiblity antigenscell surface proteins that participate in self-recognition
incomplete dominancephenotype of heterozygote is intermediate to homozygous parents
inhibitorallele whose presence blocks expression of another trait
lethal mutationallele whose expression is fatal
modifier genesa gene whose expression alters phenotype by affecting expression of other gene alleles
monomorphica gene with only one wild-type allele
multifactorialphenotype determined by two or more factors
mutant allelesalleles generated by changes in DNA sequence
penetranceproportion of individuals with a given phenotype exhibiting the expected phenotype
permissive rangeenvironmental conditions that generate a particular phenotype
phenocopychange in phenotype caused by environmental conditions - mimics mutation
pleiotropysingle gene determines a number of unrelated traits
polygenictraits controlled by multiple genes
polymorphicgenes with more than one wild-type allele
quantitative traitsanother name for continuous traits
recessive epistasiswhen a recessive allele masks the expression of another gene
recessive lethalgene allele that is fatal only in the homozygous condition
restrictive rangeenvironmental conditions that prevent expression of a given phenotype
wild-type allelethe designated "normal" gene allele


Professor of Biology
Park University
Parkville, MO

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