| A | B |
| prairie schooner | Wagon |
| Oregon Trail | Path/road that pioneers took to get to Oregon |
| pioneers | First people to move into a new territory/area |
| emigrants | People who move from one place to another (within the same country) |
| Ox | Large animal that pulled the wagons |
| cholera | Disease that killed more people than anything else |
| buffalo | Large, wild animal living in the west |
| Independence Rock | In Wyoming; pioneers arrived around the 4th of July, "Independence Day" |
| Cheyenne & Pawnee | Native American tribes that lived where the Oregon Trail crossed |
| wagon train | Different families formed traveling groups |