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Linkage, Recombination and the Mapping of Genes on Chromosomes

Review of vocabulary from Chapter 4 of Hartwell, et al. Genetics: Genes to Genomes from McGraw-Hill Publishers.

AB
ascosporesordered products of fungal meioses enclosed in a sac
ascussac enclosing ordered products of fungal meisoses
centimorgan1% recombination
chiasmatacross-overs formed during homologous recombination
coefficient of coincidenceratio of observed to expected double recombinants
double crossoverstwo chromosome breakages occur between two genes
genetic linkagealleles from two genes inherited as a unit
genetic markersgenes for easily detectable traits to monitor structures
interferencecrossovers in one region affect crossovers in another region of chromosomes
linkage groupseveral genes that tend to be inherited as a unit
locusphysical location of a gene on a chromosome
mappingdetermining location and/or order of genes on a chromosome
map unit1% recombination or 1 centimorgan
nonparental ditypecombination of any two traits not seen in the P generation
ordered tetrad analysisexamination of meisosis in ascomycetes
parental ditypecombination of two traits seen in the first generation of a genetic cross
physical markersactual DNA landmark such as chromosome band or restriction endonuclease site
recombinantnot showing a parental ditype
recombinationmovement of DNA from one chromosome to another
recombination frequencyproportion of individuals showing nonparental ditype
terminalizationmovement of cross-over sites toward ends of chromosomes
tetradfour products of any meiosis
two point crossfiguring linkage relationship by examining two traits at a time
three point crossfiguring linkage relationships between three traits simultaneously


Professor of Biology
Park University
Parkville, MO

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