| A | B |
| astrolabe | used to determine latitude at sea |
| caravel | ship whose sails allowed them to sail into the wind |
| cartographer | map maker |
| mestizo | Spanish and Native American descent |
| mulatto | Spanish and African descent |
| peninsulares | Spanish born in Spain |
| Creole | Spanish born in the New World |
| privateer | Government sanctioned pirates |
| circumnavigate | travel all the way around the world |
| encomienda | right of the Spanish to demand labor from the native americans |
| Line of Demarcation | divided the world between Spain and Portugal |
| Columbian Exchange | movement of goods, ideas and diseases between Europe, Africa and the New World |
| Conquistador | Spanish conqueror |
| Middle Passage | crossing of slaves from Africa to the New World |
| Viceroy | governor of Spanish colonies |
| Council of Indies | Law-making body of Spanish Colonial Government |
| Spice Islands | Desired destination of many explorers |
| Arabs and Italians | Groups European Explorers sought to bypass by going around Africa |
| Silk Road | overland route from Asia to Europe |
| Constantinople | city that was the center of trade prior to the Age of Exploration |