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Diseases of the Urinary system

AB
Azotemiais elevation of blood urea nitrogen and creatinine levels with no clinical manifestations
Acute Nephritic Syndrome manifestsacute onset of gross hematuria, proteinuria and hypertension
Nephrotic syndrome manifestsheavy proteinuria ( > 3.5 gm/day)
Asymptomatic hematuria or proteinuria are usually manifestation ofsubtle or mild glomerular abnormalities
Acute renal failure is manifested byoliguria or anuria with recent onset of azotemia
Nephrolithiasis (renal stones) usually manifest byrenal colic and hematuria
An ectopic ureter could be joining structures likein the proximal urethra, ejaculatory duct, seminal vesicle, and vas deferens
The most common cause of hydronephrosis in both infants and children isureteropelvic junction obstruction
A congenital megaureter is usually associatedwith hydronephrosis
Proximal causes of ureteral obstruction tend to beunilateral
Distal causes of ureteral obstruction tend to bebilateral
In most cases, transitional cell carcinoma of the ureter or renal pelvis requiresradical nephroureterectomy
Exstrophy is:absence of a portion of the lower abdominal wall and the anterior wall of the bladder
The short urethra in females increases the risk during pregnancy of developingcysitis
Acute and chronic cystitis of the urinary bladder arethe most commonly encountered clinical disorder of this organ
Hunner ulcer is:a persistant disorder of unknown cause, refractory to all forms of therapy, and typically affects middle-aged women
Malakoplakia is a bladder disorder that showsmacrophage-containing mucosal plaques and abundance of Von Hansemann cells
Cystic lesions of the urinary tract are characteized by formingsolid Brunn nests
Cystitis cystica occurrs in about60% of otherwise normal adult bladders
Transitional cell carcinomas highest frequencies occurs amongurban whites in the United States and Western Europe
80% of bladder cancer cases arebetween 50 and 80 years old
The term carcinoma in situ of the unrinary bladder is reserved fora full-thickness, malignant changes confined to the flat urothelium
Smokers are confronted withdoubling of the incidence of bladder carcinoma
Bladder cancer has been associated withoccupational exposure to certain organic chemicals
Histologically, transitional cell carcinomas are graded according totheir degree of differentiation
Metastases of bladder cancer occur in pelvic structures and could extend tothe periaortic lymph nodes, liver, lung, and bone
Squamous cell carcinoma of the urinary bladder is distinctly common inthe Middle East where schistosomiasis is endemic
Regardless of the cause of the obstruction, there is alwaysdilatation, muscular hypertrophy, diverticula and, trabeculation of the mucosal surface
The classic cause of urethritis is infection byNeisseria gonorrhoeae
the most common casuses of urethritis results from infection byChlamydia, E. coli, and Mycoplasma
In males, urethritis typically complicatesprostatitis
In females, urethritis usually followscystitis
Regardless of the cause, urinary frequency, dysuria, and urethral discharge characterizeurethral inflammation
Urethritis, arthritis, and conjunctivitis are characteristic features ofReiter syndrome
A urethral caruncle is aninflammatory lesion near the female urethral meatus that produces pain and bleeding
The autosomal dominant polycystic kidney diseaseis the cause of about 10% of all transplant/dialysis patients
Acute Poststreptococcal Glomerulonephritis is caused byautoimmune reaction to group A beta hemolytic streptococci
(40%) of nephrotic syndrome in adults are caused bymembranous nephtopathy
Diabetic glomerulosclerosisthe leading cause of renal failure in the USA
Berger diseaseis the most common form of Glomerulonephritis in the 15-30 age group
Acute tubular nephrosis could be induced byrenal hypoperfusion and nephrotoxins
rhabdomyolysis and hemolysis could induceacute tubular nephrosis
Chinese herbs nephropathy is caused byaristolochic acid
NSAIDsare the most common class of drugs responsible for renal injuries
the most common casue of acute pyelonephritisis infection by E. coli
Tha milk-alkali syndrome usually lead torenal stones due to hypercalciuria ad hypercalcemia
Secondary calcium renal stone formations are mostly a complication ofhyperparathyroidism
the most common renal stones are made ofcalcium oxalate or phosphate
Uric acid stonesare radiolucent
Calcium oxalate and phosphate stonesare radio-opaque
Metabolic acidosis with increase in the levels of P,K, BUN, Cr. are detected duringuremia
Renal cell carcinoma isthe most common kidney tumor
the use of Tobacco increases the risk forrenal cell carcinoma
Wilm's Tumor isthe most common abdominal solid tumor in childhood
Hematuria most common symptom ofcarcinoma of the kidney(50%)


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