| A | B |
| circumnavigate | to sail around the world |
| Columbian Exchange | people, plants, and animals that traveled across the Atlantic after Columbus |
| plantation | a large farm where one crop is grown |
| immunity | to have resistance to a disease |
| conquistador | a Spanish soldier |
| ambush | to attack by surprise |
| navigation | plotting and controlling the course of a ship |
| privateer | a captain of an armed, privately owned ship |
| armada | fleet |
| Northwest Passage | a water route through North America |
| enslaved | forced into slavery |
| slavery | a system in which people work without pay and had no freedom |
| rebel | to resist authority |
| legend | a story handed down from earlier times |
| invasion | conquering by force |
| settlement | a new community |
| epidemic | the spread of disease among people |