IB NUCLEIC ACID REVIEW
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  1. Exons are the genes that
    Code for defective genes
    Code for mutations
    Code for protein synthesis
    Do not code for proteins


  1. If a protein is made of 150 amino acids, then the number of codons on the mRNA strand is

    50
    150
    450
    600


  1. If a protein is made of 100 amino acids, then the number of nucleotides on the mRNA is

    100
    200
    300
    600


  1. If the number of nucleotides on mRNA is 600, then the number of amino acids that it can code for is

    100
    200
    300
    600


  1. If the number of nucleotides on mRNA is 600, then the number of anticodons involved in transcription is

    100
    200
    300
    600


  1. A chromosome is made of DNA and
    Carbohydrates
    RNA
    Proteins
    Lipids


  1. The 3’ to 5’ direction of a DNA strand refers to the position of
    Hydrogen in the ribose of each nucleotide
    Carbon in the deoxyribose of each nucleotide
    Nitrogen in the nitrogen base
    Phosphates in the whole chain


  1. During DNA replication, the new nucleotides that start binding with the unpaired nucleotide arrive as

    Nucleoside diphosphate
    Nucleoside triphosphate
    Nucleoside 5 phosphate
    Nucleoside 6 phosphate


  1. The energy needed for building the new chain is produced from breaking
    DNA nucleotide
    ATP
    2 phosphates from a nucleoside triphosphate
    Hydrogen bonds


  1. Topisomerase is an enzyme involved in DNA replication, it functions in
    Breaking hydrogen bonds
    Relieving the super coiling of the two DNA chains
    Growing a new chain
    Preventing rejoining of the two DNA chains


  1. DNA replication is needed for
    Mitosis only
    Meiosis only
    Mitosis and meiosis
    Either mitosis or meiosis depending on the type of cell


  1. In DNA replication the new chain grows in a
    3' to 5' direction
    5' to 3' direction
    Any direction
    Depends on Okazaki fragments


  1. The leading strand in DNA replication is the strand that
    Grows in fragments
    Grows continuously
    Dictates the sequence
    Causes mutation


  1. After replication, the daughter DNA molecules
    Have all their nucleotides from the parent DNA
    One strand contains only parental nucleotides and the other is assembled newly
    Each strand contains a mixture of parental and newly assembled nucleotides.
    The two strands contain nucleotides randomly assembled.


  1. In DNA replication the nucleotides are added to the following position of the growing strand

    The 3' position
    The 5' position
    Any position
    The 3' and 5' positions


  1. During replication the first bit that starts the new strand is
    DNA primer
    RNA primer
    Polymerase
    Amino acids


  1. The enzyme that breaks the hydrogen bonds between the two DNA strands is called

    RNA polymerase
    DNA polymerase
    Ligase
    Helicase


  1. The Okazaki fragments are connected by
    RNA polymerase
    DNA polymerase
    Helicase
    Ligase


  1. DNA replication precedes
    Mitosis only
    Meiosis only
    Mitosis and meiosis
    Depends on the number of chromosomes


  1. DNA replication occurs in the
    Nucleus
    Cytoplasm
    Extracellular fluid
    On the ribosome surface


  1. The two daughter DNA molecules resulting from replication are
    Identical to RNA
    Identical to the parent DNA
    Made of one strand each
    Made of uracil instead of thymine


  1. Translation results in the formation of
    mRNA
    tRNA
    rRNA
    Polypeptide


  1. The DNA triplet that results in an anticodon of UUU is
    AAA
    CCC
    GGG
    TTT


  1. Sickle cell anaemia is due to
    Deletion
    Inversion
    Substitution
    Addition


  1. Transcription occurs in the
    Cytoplasm
    Cell membrane
    Ribosomes
    Nucleus


  1. Transcription results in the formation of
    RNA
    RNA and DNA
    Ribosomes
    Amino acids


  1. In transcription the RNA strand grows in a
    3' to 5' direction
    5' to 3 direction
    Any direction
    Okazaki fragments


  1. Translation starts from the
    3' end of mRNA
    5' end of mRNA
    3' end of tRNA
    5' end of tRNA


  1. During translation the surface of one ribosome can be occupied by
    One codon
    Two codons
    Three codons
    Four Codons


  1. The amino acid is added to the
    A site of the smaller ribosome subunit
    P site of the smaller ribosome subunit
    A site of the larger ribosome subunit
    P site of the larger ribosome subunit


  1. The genetic code is described as degenerate because
    Each codon can code for more than one amino acid
    The same codon codes for the same amino acid in all organisms
    Some codons are nonsense codons
    One amino acid can have more than one codon


  1. Nonsense codons code for
    Many amino acids
    The same amino acid
    Non specific amino acids
    No amino acids


  1. Except for uracil instead of thymine, mRNA is
    The same sequence as the template DNA strand
    The same sequence as the inactive DNA strand
    Complementary sequence to the ribosomal RNA
    Complementary sequence to the inactive DNA strand


  1. The active DNA strand runs in a
    3' to 5' direction
    5' to 3' direction
    Any direction
    Similar to its complementary chain


  1. If a DNA molecule has 1000 nucleotides out of which 200 are thymine, what is the percentage of cytosine.

    20
    30
    40
    60


  1. After DNA is synthesized on the ribosomes it is packaged in the
    Cristae and sent to the Golgi Complex
    Stroma and modified by the Golgi complex
    Vesicles and modified by the RER
    Cisternae and sent to the Golgi complex


  1. What is the composition of the backbone of DNA?
    Alternating sugar and phosphate molecules
    Complementary base pairs
    Alternating sugar and base molecules
    A polysaccharide


  1. Which of the following are connected by a hydrogen bond?
    The hydrogen and oxygen atoms of a water molecule
    A base pair of a DNA molecule
    Two amino acid molecules of a dipeptide
    Two glucose molecules in a disaccharide


  1. To which parts of the deoxyribose molecule do phosphates bind in DNA?
    I and V
    III and IV
    II and III
    III and V


  1. What is the function of helicase?
    It forms bonds between DNA nucleotides.
    It adds new nucleotides to the DNA helix.
    It forms the DNA helix.
    It separates DNA strands.


  1. Which enzyme removes the RNA primer during replication?
    RNA primase
    DNA polymerase I
    DNA ligase
    Helicase


  1. The diagram below shows a short section of DNA molecule before and after replication. If the nucleotides used to replicate the DNA were radioactive, which strands in the replicated molecules would be radioactive?

    II and III only
    I and III only
    I and II only
    I, II, III and IV


  1. A biochemist isolated and purified molecules needed for DNA replication. When some DNA was added replication occurred, but the DNA molecules formed were defective. Each consisted of a normal DNA strand paired with segments of DNA a few hundred nucleotides long. Which of the following had been left out of the mixture?
    DNA ligase
    Helicase
    Nucleotides
    DNA polymerase





Mrs. Kelli Trask and Mrs. Lisa Boulden
Biology Teacher
Lee's Summit West High School
Lee's Summit, MO