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Chapter 12 Vocabulary: Human Genetics

AB
sex chromosomechromosomes that determine sex (XX or XY)
autosomeall chromosomes in an organism that do not determine sex
sex-linked traita trait that has alleles on the sex chromosomes
linked genepairs of genes that tend to be inherited together
chromosome mapa linear diagram of a chromosome with location of genes on it
map unitan increment of 1% in crossing over on a chromosome
germ-cell mutationsmutations that occur in an organism's gametes
somatic-cell mutationsmutations that occur in an organism's body cells
lethal mutationa mutation that causes death...usually before birth
deletionloss of a piece of chromosome
inversiona piece of chromosome breaks off, flips, and reattaches
translocationa piece of chromosome breaks off and reattaches to a nonhomologous chromosome
nondisjunctionwhen homologous chromosomes don't separate during meiosis
point mutationsubstitution, addition, or removal of a single nucleotide
substitutionone nucleotide replaces another
frameshift mutationwhen a deletion or addition causes incorrect grouping downstream on the DNA
insertion mutationone or more nucleotides added to a gene
pedigreea diagram that shows how a trait is inherited over several generations
carrierhave one copy of the recessive allele, but not the trait/disease
genetic disorderdiseases or conditions that have a genetic basis
polygenictraits determined by many genes (eye color/skin color)
complex charactertraits influenced by many genes and the environment (skin color)
multiple allelegenes with more than two alleles like blood type
codominancewhere both alleles are expressed in a heterozygote (AB blood type)
incomplete dominancea trait where two alleles "blend" (wavy hair)
sex-influenced traitwhere alleles may be influence by hormones (pattern baldness)
Huntington's Diseaseautosomal dominant disease that effect's a persons motor and mental abilities
amniocentesisanalyzing amniotic fluid to test for genetic disorders
chorionic villi samplingtaking a sample of the chorionic villi cells to test for genetic disorders
genetic counselinga person that tells a couple about genetic disorders
gene therapya technique to replace a defective gene with a healthy one


Teacher of Forensic Science and A.P. Environmental Science
Brick Township High School
Brick, NJ

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