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Mendelian Genetics

Intro to Mendelian Genetics

AB
allelepart of a gene that codes for a physical trait: one of a number of different forms of a gene that contributes to a particular genotypic or phenotypic trait
chromosomea thread-like structure made of molecules within the nucleus that contains genetic information that is passed from one generation to the next
codominancethe phenotypes produced by both alleles are completely expressed together (black fur parent + white fur parent = offspring with spots of each color)
crossing-overprocess in which homologous chromosomes exchange portions of their chromatids during meiosis, thereby shuffling genes between homologous chromosomes
diploida cell that contains 2 sets of homologous chromosomes (2n) - 46 in humans
gametesex cell, such as a sperm or an egg
genea sequence of DNA that codes for/determines a specific trait
genotypegenetic make-up of an organism in terms of alleles present
haploidcell that contains 1 set of chromosomes: 1n - (23) in humans
heterozygoushaving 2 different alleles for a particular gene
homologouspairs of chromosomes in which 1 set (23) of chromosomes comes from the mother and 1 set (23) of chromosomes comes from the father
homozygoushaving 2 identical pairs of alleles for a particular gene
incomplete dominanceone allele is not completely dominant over the other, and phenotype results in a mixture of the 2 alleles, where the heterozygous genotype results in a new phenotype (such as red + white = pink)
meiosisthe process in which the number of chromosomes per cell is cut in half through the separation of homologous chromosomes in a diploid cell. Only happens in sex cells, not somatic cells.
phenotypethe physical characteristics of an organism that are expressed as traits
punnett squarea diagram that can be used to predict the genotypic and phenotypic outcomes for one ore more traits, of the combinations of a genetic cross between 2 parents
polygenic traita trait which involves more than one gene
Gregor Mendelan Austrian monk who through his experiments on pea plants in the early 19th century, discovered patterns in genetic inheritance
F1 generationoffspring from two true-breeding parents (PP + ww = all Pw)
genetic probabilitythe expected outcome of genotype and phenotype, depending on the chance of choices of traits in offspring occurring
calculating genetic probabilityif there is a 50-50% chance, multiply 1/2 to the exponent of the number of outcomes (ex: the odds of having 5 girls in a row is shown as 1/2 to the 5th power (answer: odds are 1/32)
F2 generationthe offspring of F1 generation parents (usually resulting in a 3:1 phenotypic outcome and a 1:2:1 genotypic outcome)
normal alleleform of a gene that codes for the normal sequence of amino acids making the correct protein
Mendel's 3 Laws (Mendelian Genetics)Law of Heredity; Law of Independent assortment; Law of Dominance
Law of Segregationalleles separate into gametes randomly
Law of Independent AssortmentGenes for different traits mix randomly in gametes
Law of DominanceSome alleles are dominant over other alleles
number of daughter cells produced in mitosis2
number of daughter cells produced after meiosis4
zygotea fertilized egg
tetradformed during the first phase of meiosis - the two homologous chromosomes will align next to each other (each is made up of two sister chromatids it will look like a group of four)
hybridoffspring from a true-breeding cross - example: purple (PP) x white pea (pp) flowering plants = Pp
multiple allele traita trait contolled by many alleles in one gene (base pair changes)


math & science teacher
Academy of the New Church Girls School
Bryn Athyn, PA

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