| A | B |
|---|
| The DNA viruses are remembered by what mnemonic? | HHHAPPPy |
| All DNA viruses are [BLANK] in shape except for Pox? | Icosahedral |
| Pox has what type of shape? | Complex |
| 3 DNA HHHAPPy viruses are happy because they are [BLANK]? | Clothed (enveloped) |
| What 3 DNA viruses are clothed (enveloped)? | Hepadna, Pox, & Herpes |
| What 3 DNA viruses are naked? | Human Papilloma, Adeno, & Polyoma |
| What disease does Herpes simplex virus type I (HHV-1) lead to? | Oral, ocular lesions (fever blisters); encephalitis |
| What disease does Herpes simplex virus type 2 (HHV-2) lead to? | Genital, anal lesions (severe/ fatal neonatal) |
| What disease does Varicella zoster virus (HHV-3) lead to? | Chickenpox; shingles |
| What disease does Epstein-Barr virus (HHV-4) lead to? | Infectious Mononucleosis (IM); Tumors |
| What disease does Cytomegalovirus (HHV-5) lead to? | IM; Congenital infections; infections in allograft recipients (pneumonia) |
| What disease does Human herpesvirus 6A (HHV-6) lead to? | Some infections in allograft recipients and AIDS patients (pneumonia, marrow failure, encephalitis) |
| What disease does Human herpesvirus 6B (HHV-6) lead to? | Roseola in infants; infections in allograft recipients (pneumonia, marrow failure) |
| What disease does Human herpesvirus 7 (HHV-7) lead to? | Some cases of roseola |
| What disease does Human herpesvirus 8 (HHV-7) / Kaposi sarcoma-associated virus lead to? | Tumors: Kaposi’ sarcoma; some B cell tumors |
| Parvoviridae is a [BLANK] stranded DNA virus | Single |
| Is parvoviridae an enveloped or naked DNA virus? | Enveloped |
| What shape is parvoviridae? | Icosahedral |
| Parvoviridae causes what condition? | Erythema infectiosum (fifth disease / slapped cheek syndrome) |
| Paroviridae is found in what type of patients? | Patients with sickle cell (aplastic anemia) |
| Papillomavirinae is a [BLANK] stranded DNA virus | Double |
| Is Papillomavirinae an enveloped or naked DNA virus? | Naked |
| What shape is Papillomavirinae? | Icosahedral |
| What condition does Papillomavirina cause? | Warts |
| Papillomavirina has over [BLANK] species? | 100 |
| What types of HPV cause cervical cancer? | 16 & 18 |
| How is HPV contracted? | How is HPV contracted? |
| What types of HPV cause genital warts? | 6 & 11 |
| What is the most common viral STD in the USA? | HPV 6 & 11 |
| What condition does HPV 6 & 11 cause? | Condyloma acuminate (Cauliflower) |
| What causes common warts? | HPV 1, 2, & 4 |
| What is Verruca vulgaris? | Wart on the hand |
| What is Plantar wart? | Wart on the foot |
| Adenovirus is a [BLANK] stranded DNA virus | Double |
| Is Adenovirus an enveloped or naked DNA virus? | Naked |
| What shape is Adenovirus? | Icosahedral |
| What conditions are caused by the Adenovirus? | Conjunctivitis (red eye) & Acute febrile pharyngitis |
| Paolyomavirinea has only [BLANK] human viruses? | Two |
| How is Paolyomavirinea spread? | Transmitted by droplets from upper respiratory tract |
| What are the types of Paolyomavirinea? | BK & JC |
| What does BK Paolyomavirinea cause? | Progressive multifocal leukoencephalopathy in immunocompromised patients |
| What does JC Paolyomavirinea cause? | Cystitis in immunocompromised patients |
| What are the three enveloped DNA viruses? | Hapadna, Pox, & Herpes |
| Hepadnaviridae is a [BLANK] stranded DNA virus | Double |
| What shape is Hepadnaviridae? | Icosahedral |
| Is Hepadnaviridae an enveloped or naked DNA virus? | Enveloped |
| What condition does Hepadnaviridae cause? | Hepatitis B |
| How is Hepadnaviridae transmitted? | Sex, Dirty Needles, & Breast Milk |
| What symptoms does Hepadnaviridae cause? | Jaundice, hepatomegaly, dark urine |
| Poxviridae is a [BLANK] stranded DNA virus | Double |
| Is Poxviridae an enveloped or naked DNA virus? | Enveloped |
| What shape is Poxviridae? | Complex |
| Poxviridae causes what condition? | Poxviridae causes what condition? |
| What is another name for Variola virus | Smallpox |
| How many serotypes does Variola virus have? | One |
| How is Variola virus transmiteed? | Aerosol droplets or direct contact |
| Variola virus has a [BLANK] mortality rate | 1/3 |
| What does Molluscum contagiosum cause? | Small, pink cup shaped papules (umbilication) |
| Molluscum contagiosum affects what age groups? | Adults & children |
| How is Molluscum contagiosum transmitted? | Direct contact |
| How many types of Herpesviridae are pathogenic to humans? | 8 |
| Herpesviridae is a [BLANK] stranded DNA virus | Double |
| What shape is Herpesviridae? | Icosahedral |
| Is Herpesviridae an enveloped or naked DNA virus? | Enveloped |
| What forms of Herpesviridae are classified under the subfamily Alphaherpesvirinae? | Herpes simplex 1, Herpes simplex 2, & Varicella-zoster virus |
| What forms of Herpesviridae are classified under the subfamily Betaherpesvirinae? | Human cytomegalovirus, Human herpesvirus 6, & Human herpesvirus 7 |
| What forms of Herpesviridae are classified under the subfamily Gammaherpesvirinae? | Epstein-Barr virus & Human herpesvirus 8 |
| All forms of Herpesviridae have a [BLANK] phase | Latent |
| How is Human Herpes Virus 1 transmitted? | Direct contact |
| Human Herpes Virus 1 is also known as [BLANK]? | Herpes labialis, cold sores, fever blisters |
| Where does Human Herpes Virus 1 lay dormant? | Trigeminal ganglia |
| How is Human Herpes Virus 2 transmitted? | Direct contact |
| What does How is Human Herpes Virus 2 cause? | Recurrent painful lesions on the genitals |
| Where does Human Herpes Virus 1 lay dormant? | Sacral or lumbar ganglia |
| Viruses that are part of the TORCHS complex have what common characteristic? | Spread from mother to newborn |
| What does the T in the TORCHES complex stand for? | Toxoplasmosis |
| What does the O in the TORCHES complex stand for? | Others like HIV and Hepatitis B |
| What does the R in the TORCHES complex stand for? | Rubella |
| What does the C in the TORCHES complex stand for? | Cytomegalovirus |
| What does the H in the TORCHES complex stand for? | Herpes |
| What does the S in the TORCHES complex stand for? | Syphilis |
| All TORCHES Complex viruses, except Herpes, are transmitted from mother to child via the [BLANK]? | Placenta |
| Human Herpes Virus 3 is also known as [BLANK]? | Varicella-zoster virus |
| Varicella-zoster virus is also known as [BLANK]? | Chicken Pox |
| How is Varicella-zoster virus transmitted? | Respiratory droplets or direct contact |
| When is Varicella-zoster virus contagious? | 2-3 days before the rash develops until the blisters have crusted over? |
| Shingles is a reactivation of [BLANK]? | Varicella-zoster virus |
| Varicella-zoster virus lies dormant in the [BLANK]? | Dorsal Root Ganglia |
| What does Shingles present with? | Dermatomal painful vesicles (hyperalgesia) |
| How long can Post zoster neuralgia can last for? | Months |
| Human Herpes Virus 4 is also known as [BLANK]? | Epstein-Barr Virus |
| How is Epstein-Barr Virus spread? | Exchange of Saliva |
| Epstein-Barr Virus is most commonly associated with [BLANK]? | Infectious mononucleosis (aka the kissing disease |
| What are the symptoms of Mononucleosis? | Fatigue, fever, pharygitis, lymphadenopathy |
| What type of cancer is Epstein-Barr Virus associated with? | Burkitt lymphoma |
| What is Burkitt lymphoma? | Malignancy of the nasopharyngeal area (often the jaw) |
| Starry sky appearance on lymph node biopsy is characteristic of [BLANK]? | Burkitt lymphoma |
| What conditions is Human Herpes Virus 4 associated with? | Infectious mononucleosis, Burkitt lymphoma, & Hairy leukoplakia |
| What is Hairy Leukoplakia? | White lesions on the tongue |
| Hairy Leukoplakia is seen in {BLANK] | AIDS patients infected with HHV4 |
| Human Herpes Virus 5 is also known as [BLANK]? | Cytomegalovirus |
| How do children transmit Human Herpes Virus 5? | Saliva & Urine |
| How do children transmit Human Herpes Virus 5? | Blood & Sex |
| What virus is responsible for the most common cause of birth defects in the USA? | Human Herpes Virus 5 |
| Human Herpes Virus 5 can cause damage to [BLANK}? | Kidney, Spleen, & Nervous System (blind, deaf) |
| Human Herpes Virus 6 & 7 cause what condition? | Roseola infantum (6th disease) |
| How is Human Herpes Virus 6 & 7 transmitted? | Saliva |
| What are the symptoms of Roseola infantum? | 3-5 days of very high fever, a fine red rash appears on the neck and trunk, & potential Febrile seizure |
| What is the most recognizable symptoms of Roseola infantum? | A fine red rash appears on the neck and trunk |
| Human Herpes Virus 8 can cause what condition? | Kaposi sarcoma |
| How is Human Herpes Virus 8 transmitted? | Sex |
| Human Herpes Virus 8 can lead to malignancy in [BLANK]? | Opportunistic individuals (ie. AIDS patients) |
| What does Human Herpes Virus 8 present with? | Purple lesions, often raised, found on the skin of arms, legs and mouth |
| What are the tumor causing DNA viruses? | Human Papilloma virus, Epstein-Barr virus, Hapatitis B virus, Human Herpes virus 8, Hepatitis C – RNA virus that predisposes person to hepatocellular carcinoma |
